The honest answer on STEP 3 is that it depends, and the useful part is the list of what it depends on. Four items, in rough order of how much they matter. Most people get the first two right and then argue about the fourth.
The question in the title: Journal club: STEP 3 and the intensive behavioural therapy floor — does this still hold? I will give what I have already checked below so nobody repeats it.
Asking about STEP 3 on behalf of the question I keep seeing asked badly, including by me.
Framed properly it is answerable. Framed the usual way it is not, and that is most of why the previous threads went nowhere.
The honest answer on STEP 3 is that it depends, and the useful part is the list of what it depends on. Four items, in rough order of how much they matter.
Most people get the first two right and then argue about the fourth.
STEP 1 (N Engl J Med 2021): The pivotal obesity trial for semaglutide and the reference point for most subsequent comparison. Mean weight reduction was substantially larger than anything previously achieved pharmacologically.
Worth checking against a second source before it gets quoted onward.
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