Adolescents: a distinct evidence base Writing it up because I had to work it out twice and would rather nobody else did.
What changes if the standard account of adolescents is wrong? I ask because I have been treating it as settled and I noticed this week that I could not say why.
Working through the consequences rather than the evidence, since others here are better placed on the evidence.
The opening post is the version of this I will quote in future. One addition.
Genetic and ancestry-related differences in response are asked about regularly and the published evidence is thin enough that the honest answer is short.
Happy to expand any of that if it is the useful part.
Adolescents: a distinct evidence base exists. The compounds are not approved for routine adolescent obesity but are being studied. Adolescent physiology and psychology differ from adults' in ways that matter for this medication class.
Posting it because the silence on this was starting to look like agreement.
Adolescent evidence exists for some compounds in this class and is a separate approval decision with its own trials rather than an extension of the adult data.
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