20 categories

Clinical

Laboratory interpretation, comorbidities, special populations, and preparing for a conversation with your own prescriber. General information only.

96 topics4,480 posts30 solved Moderators: bench_notes, hana.sato About this category

Bloodwork 30 Comorbidities 24 Special populations 22 Prescriber conversations 20

96 topics · page 1 of 4

Topic	Participants	Replies	Views	Activity
About the Comorbidities category Clinical › Comorbidities type 2 diabetes chronic kidney disease MASH / hepatic steatosis Pinned Wiki Type 2 diabetes, hepatic steatosis, sleep apnoea, cardiovascular and renal disease. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its author…		4	16k	12h
Second pass at: When your prescriber and the evidence disagree Clinical › Prescriber conversations beginner friendly type 2 diabetes telehealth prior authorisation Pinned Second pass at: When your prescriber and the evidence disagree — setting out what I have, and where I think it stops being reliable. What changes if the standard account of prescriber is wrong? I ask because…	+51	55	9.2k	2d
Adolescents: a distinct evidence base — one year on Clinical › Special populations bariatric surgery history disordered eating pregnancy & planning adolescents Pinned Wiki Posting this under the heading it deserves: Adolescents: a distinct evidence base — one year on Everything below is what sits behind that. A methods question rather than a substantive one, about Adolescents.…	+78	88	9.3k	3mo
About the Bloodwork category Clinical › Bloodwork HbA1c lipid panel eGFR & renal function Pinned Wiki Panels, reference intervals, biological variation, and resisting the urge to over-read one result. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded…	+4	8	4.4k	3mo
About the Special populations category Clinical › Special populations older adults pregnancy & planning adolescents Pinned Wiki Older adults, pregnancy and pregnancy planning, adolescents, renal and hepatic impairment, bariatric surgery history. This post is a community wiki: any member at trust level 3 or above can edit it, and every…		4	3k	4mo
Hepatic impairment and the absence of data — a second dataset Clinical › Special populations adolescents disordered eating pregnancy & planning older adults Pinned On the subject in the title: Hepatic impairment and the absence of data — a second dataset Working notes rather than a conclusion. Posting a small dataset on Hepatic impairment. It is mine, it is…		2	4.3k	4mo
Lipase elevation without symptoms: the interpretation problem Clinical › Bloodwork thyroid function lipase & amylase eGFR & renal function Pinned Closed Lipase elevation without symptoms: the interpretation problem Writing it up because I had to work it out twice and would rather nobody else did. Lipase elevation without symptoms — I have the observation and…	+21	25	62k	5mo
About the Prescriber conversations category Clinical › Prescriber conversations telehealth prior authorisation beginner friendly Pinned Wiki How to prepare for an appointment, what to bring, and how to ask for what you need without antagonising anyone. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit…	+6	11	9.5k	9mo
Coming back to: Bariatric surgery history: altered anatomy, altered expectations Clinical › Special populations adolescents disordered eating older adults Pinned Bariatric surgery history: altered anatomy, altered expectations Writing it up because I had to work it out twice and would rather nobody else did. Bariatric surgery history — I have the observation and I do…		2	38k	15mo
Athletes in weight-category sports: a different risk calculus — a second dataset Clinical › Special populations pregnancy & planning disordered eating bariatric surgery history Pinned On the subject in the title: Athletes in weight-category sports: a different risk calculus — a second dataset Working notes rather than a conclusion. Posting a small dataset on Athletes in weight-category…	+37	41	16k	20mo
eGFR fluctuation and the creatinine denominator problem — the long version Clinical › Bloodwork thyroid function eGFR & renal function liver enzymes lipase & amylase Under review eGFR fluctuation and the creatinine denominator problem — the long version — setting out what I have, and where I think it stops being reliable. A narrow question about egfr fluctuation, deliberately narrow,…	+43	47	17k	just now
Reference intervals: how they are constructed and why one in twenty flags — does this still hold? Clinical › Bloodwork thyroid function liver enzymes lipid panel HbA1c Solved Asking directly, because I could not find a straight answer: Reference intervals: how they are constructed and why one in twenty flags — does this still hold? A methods question rather than a substantive one,…	+18	22	281	2h
Revisiting: Liver enzymes drifting down and what that usually means Clinical › Bloodwork thyroid function eGFR & renal function liver enzymes lipase & amylase On the subject in the title: Revisiting: Liver enzymes drifting down and what that usually means Working notes rather than a conclusion. A methods question rather than a substantive one, about Liver enzymes…	+55	61	39k	3h
What to bring: records that a clinician can actually use — a second dataset Clinical › Prescriber conversations telehealth beginner friendly prior authorisation What to bring: records that a clinician can actually use — a second dataset I have a specific reason for asking rather than idle curiosity, and the context is below. A question about how to describe something…	+80	86	5.6k	3h
Adolescents: a distinct evidence base Clinical › Special populations older adults pregnancy & planning adolescents chronic kidney disease Adolescents: a distinct evidence base Writing it up because I had to work it out twice and would rather nobody else did. What changes if the standard account of adolescents is wrong? I ask because I have been…		3	11k	9h
Lipid changes during rapid weight loss: the expected trajectory Clinical › Bloodwork liver enzymes thyroid function lipid panel lipase & amylase Solved Posting this under the heading it deserves: Lipid changes during rapid weight loss: the expected trajectory Everything below is what sits behind that. Lipid changes during rapid weight: what I expected, what…	+11	15	34k	11h
Osteoarthritis and mechanical versus metabolic improvement Clinical › Comorbidities MASH / hepatic steatosis chronic kidney disease type 2 diabetes obstructive sleep apnoea Osteoarthritis and mechanical versus metabolic improvement Writing it up because I had to work it out twice and would rather nobody else did. Asking about osteoarthritis and mechanical versus metabolic…	+2	6	30k	12h
HbA1c lag and what it can and cannot tell you at eight weeks — one year on Clinical › Bloodwork liver enzymes lipase & amylase lipid panel thyroid function Posting this under the heading it deserves: HbA1c lag and what it can and cannot tell you at eight weeks — one year on Everything below is what sits behind that. A methods question rather than a substantive…	+18	22	655	13h
Fasting versus non-fasting and which tests care Clinical › Bloodwork eGFR & renal function lipase & amylase HbA1c Solved Fasting versus non-fasting and which tests care Writing it up because I had to work it out twice and would rather nobody else did. Fasting versus non-fasting: what I expected, what I found, and the gap…	+72	78	14k	19h
What a good consultation looks like from the other side Clinical › Prescriber conversations prior authorisation telehealth type 2 diabetes beginner friendly What a good consultation looks like from the other side — that is the question, and I have not found it answered plainly anywhere I have looked. Something about good consultation does not reconcile and I…	+57	62	4.9k	22h
Type 2 diabetes and the largest part of the evidence base — does this still hold? Clinical › Comorbidities type 2 diabetes chronic kidney disease PCOS blood pressure Solved Type 2 diabetes and the largest part of the evidence base — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Trying to work out what would count…	+17	22	4.5k	1d
Type 1 diabetes: off-label use and the evidence gap Clinical › Special populations pregnancy & planning bariatric surgery history disordered eating Solved On the subject in the title: Type 1 diabetes: off-label use and the evidence gap Working notes rather than a conclusion. Type 1 diabetes, and specifically the version of it that the documentation does not…		2	2.3k	1d
Athletes in weight-category sports: a different risk calculus Clinical › Special populations older adults adolescents disordered eating chronic kidney disease Solved Athletes in weight-category sports: a different risk calculus — setting out what I have, and where I think it stops being reliable. Something about athletes in weight-category sports does not reconcile and I…	+38	42	6.6k	1d
PCOS and metabolic overlap: what is and is not studied Clinical › Comorbidities chronic kidney disease MASH / hepatic steatosis obstructive sleep apnoea type 2 diabetes On the subject in the title: PCOS and metabolic overlap: what is and is not studied Working notes rather than a conclusion. PCOS and metabolic overlap, from the point of view of someone who has read the…		3	6.6k	1d
What to bring: records that a clinician can actually use Clinical › Prescriber conversations beginner friendly type 2 diabetes prior authorisation Solved Asking directly, because I could not find a straight answer: What to bring: records that a clinician can actually use A question about how to describe something to a clinician rather than about the thing…	+15	19	6.4k	1d
[2026 update] Second opinions: how to seek one without burning the first Clinical › Prescriber conversations prior authorisation beginner friendly type 2 diabetes Solved On the subject in the title: Second opinions: how to seek one without burning the first Working notes rather than a conclusion. Two things I would like separated before anyone answers on Second opinions,…		2	5.9k	1d
Coming back to: Preparing for an appointment: one page, three questions Clinical › Prescriber conversations telehealth beginner friendly type 2 diabetes prior authorisation Preparing for an appointment: one page, three questions — setting out what I have, and where I think it stops being reliable. A question about how to describe something to a clinician rather than about the…	+51	56	1.4k	2d
Revisiting: PCOS and metabolic overlap: what is and is not studied Clinical › Comorbidities type 2 diabetes obstructive sleep apnoea PCOS Revisiting: PCOS and metabolic overlap: what is and is not studied — setting out what I have, and where I think it stops being reliable. Trying to establish the boundary conditions on PCOS and metabolic…	+55	59	26k	2d
When your prescriber and the evidence disagree Clinical › Prescriber conversations prior authorisation telehealth type 2 diabetes When your prescriber and the evidence disagree — that is the question, and I have not found it answered plainly anywhere I have looked. What changes if the standard account of prescriber is wrong? I ask…	+14	18	273	2d
A single out-of-range value on an otherwise normal panel Clinical › Bloodwork lipid panel HbA1c liver enzymes lipase & amylase Posting this under the heading it deserves: A single out-of-range value on an otherwise normal panel Everything below is what sits behind that. General question, not a request for advice about my own care — I…	+70	75	20k	6d

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