Picking up post #2: that is the part I would want checked first. Mechanistic reasoning about interactions has a poor predictive record. It is a good way to generate a question and a bad way to answer one. One of those cases where knowing the mechanism does not help the decision.
On the subject in the title: Delayed gastric emptying and oral medication absorption: which drugs matter — one year on Working notes rather than a conclusion.
A follow-up question about Delayed gastric emptying and oral that I did not know to ask the first time.
The earlier thread answered what I asked. What I should have asked is below, and I think it is the one that matters.
Timing separation is the standard mitigation where absorption rate is the concern, and the interval that matters depends on the other drug rather than on this one.
I would treat that as a working assumption and revisit it.
Picking up post #2: that is the part I would want checked first.
Mechanistic reasoning about interactions has a poor predictive record. It is a good way to generate a question and a bad way to answer one.
One of those cases where knowing the mechanism does not help the decision.
Vitamins: most vitamins have no significant interaction. Fat-soluble vitamins (A, D, E, K) might be affected by the slowing of fat absorption during weight loss, but that is a nutritional consequence rather than an interaction.
Two people can read the same figure differently here and both be reasonable.
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