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Price changes over 2025 and 2026, tabulated and dated — does this still hold?

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Solved by i.bakken in post #6
Careful with the language on Price changes. "Not detected" and "not present" are different findings and the first is a statement about the method.

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WM
w.moreauTL214 Oct 2025#1

Price changes over 2025 and 2026, tabulated and dated — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below.

Documenting an access outcome, dated, because everything in this category expires.

As of January 2026, in my region, the position is as described below. I have linked the primary source rather than a summary of it, because the summaries are consistently a year behind.

If anyone can confirm or contradict this for their own region, please date your answer. An undated claim in this category is worse than no claim.

13 likes 9mo
CC
c.correiaTL218 Oct 2025#2

Taking Price changes seriously for a moment rather than deflecting: the honest position is that the community has observations and no controlled comparison, and those two things support very different sentences.

1 like 9mo
DF
d.fontaineTL221 Oct 2025#3

Worth separating two things that the opening post runs together.

List prices versus negotiated prices: the price a pharmaceutical company publishes and the price an insurance company or pharmacy actually pays differ substantially. List price is not what anyone pays.

I would hold that lightly until someone with a larger sample weighs in.

32 likes 9mo
KS
k.salinasTL223 Oct 2025#4
d.fontaine, post #3: Worth separating two things that the opening post runs together. List prices versus negotiated prices: the price a pharmaceutical company publishes and the price an insurance company or pharmacy actually pays differ substantially. List price is not what anyone pays. I would hold that lightly until someone with a larger sample weighs in. Go to post

Price variation between pharmacies: identical prescriptions can cost different amounts at different pharmacies because pharmacies negotiate individually with insurers and manufacturers.

That is the practical version. The rigorous version is longer and says the same thing.

17 likes in reply to #3 9mo
DO
dr_okonkwoTL4 Moderator25 Oct 2025#5

Two questions I would want answered before drawing anything from the Price changes data above: how were the cases selected, and what happened to the ones that dropped out.

3 likes 9mo
IB
i.bakkenTL2 Solution27 Oct 2025 · edited#6

Careful with the language on Price changes. "Not detected" and "not present" are different findings and the first is a statement about the method.

7 likes 9mo
SK
s.karlsen_rphTL3Pharmacist29 Oct 2025#7
w.moreau, post #1: Price changes over 2025 and 2026, tabulated and dated — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Documenting an access outcome, dated, because everything in this category expires. As of January 2026, in my region, the position is as described below. I have linked the… Go to post

That is consistent with mine, for whatever one more account is worth.

24 likes in reply to #1 9mo
MP
m.perrinTL231 Oct 2025#8
s.karlsen_rph, post #7: That is consistent with mine, for whatever one more account is worth. Go to post

Picking up post #5: that is the part I would want checked first.

Where a price includes consultation, device and follow-up, saying so makes a comparison possible. Most quoted figures do not.

Adding it in case it saves somebody the afternoon it cost me.

11 likes in reply to #7 9mo
VS
v.szaboTL3Analytical chemist2 Nov 2025#9
i.bakken, post #6: Careful with the language on Price changes. "Not detected" and "not present" are different findings and the first is a statement about the method. Go to post

Answering the question post #5 raises rather than the one it answers.

Where a price is quoted per vial, the fill has to be stated for the comparison to mean anything.

16 likes in reply to #6 9mo
OV
o.vukovicTL24 Nov 2025#10

Larger orders shift risk as well as price, because more of your material then comes from one lot.

Reading it back, the second half matters more than the first.

6 likes 9mo
PW
PharmNotes_WhitfieldTL4Pharmacist6 Nov 2025#11

Insurance tier placement: a compound might be covered but on a higher tier (higher copay). Moving to a lower tier usually requires prior authorization or documented failure of cheaper alternatives.

It is worth checking rather than assuming, which costs nothing.

5 likes 9mo
NK
n.kuuselaTL28 Nov 2025#12

Price changes has been discussed here with more heat than it deserves, mostly because two definitions have been in play the whole time.

14 likes 9mo
NA
n.abernathyTL3Analytical chemist9 Nov 2025#13
PharmNotes_Whitfield, post #11: Insurance tier placement: a compound might be covered but on a higher tier (higher copay). Moving to a lower tier usually requires prior authorization or documented failure of cheaper alternatives. It is worth checking rather than assuming, which costs nothing. Go to post

Confirming post #10 from a second method, which matters more than confirming it from a second person.

The most useful thing anyone has posted about Price changes in this category was a table of what had been measured and by whom. That is what I would want again.

0 likes in reply to #11 9mo
PM
p.mwangiTL211 Nov 2025#14
c.correia, post #2: Taking Price changes seriously for a moment rather than deflecting: the honest position is that the community has observations and no controlled comparison, and those two things support very different sentences. Go to post

Price differences within a market are usually about scale, documentation and logistics rather than about anything mysterious.

0 likes in reply to #2 9mo
DH
dietitian_hollisTL3Dietitian13 Nov 2025#15

On Price changes, the part that usually goes wrong is that the question is asked as though it has one answer. It has a range, and the width of the range is the interesting bit.

If you can post the two or three numbers you are working from, several people here will check the arithmetic rather than argue about the conclusion.

2 likes 8mo
EH
e.halonenTL214 Nov 2025#16

Worth separating two things that post #12 runs together.

Two claims get bundled together under Price changes and they need separating. The descriptive one — this is what was observed — is usually well supported. The causal one — this is why — usually is not.

Almost every disagreement in threads like this one dissolves once you say which of the two you are making.

9 likes 8mo
JW
journalclub_wrenTL3Regular16 Nov 2025#17

A price well below the rest of the market is a fact rather than a finding, and it is worth noting without concluding from it.

Scoping that to what I have actually seen rather than what I have read.

28 likes 8mo
YA
y.asanteTL217 Nov 2025#18
k.salinas, post #4: Price variation between pharmacies: identical prescriptions can cost different amounts at different pharmacies because pharmacies negotiate individually with insurers and manufacturers. That is the practical version. The rigorous version is longer and says the same thing. Go to post

Comparing a licensed product's price to a research-use-only preparation's price is comparing two different things, and the difference is most of the explanation.

Second-hand, so weight it accordingly.

0 likes in reply to #4 8mo
SS
steady_stateTL3Regular19 Nov 2025#19

This follows post #18 rather than contradicting it.

A cheaper option that arrives slowly has a cost in the form of running out, and people rarely price that.

13 likes 8mo
TK
t.karlsenTL220 Nov 2025#20
journalclub_wren, post #17: A price well below the rest of the market is a fact rather than a finding, and it is worth noting without concluding from it. Scoping that to what I have actually seen rather than what I have read. Go to post

Cost per milligram is the only comparison that survives format differences, but even then it needs care. A pen and a vial are not the same product and cannot be compared on price per milligram alone because dead volume, wastage, and number of doses actually obtainable differ.

27 likes in reply to #17 8mo
CH
ca.haddadTL222 Nov 2025#21

Post #17 describes the usual case. This is about the unusual one.

List prices versus negotiated prices: the price a pharmaceutical company publishes and the price an insurance company or pharmacy actually pays differ substantially. List price is not what anyone pays.

8 likes 8mo
VK
v.klausenTL3Regular23 Nov 2025#22

The most useful pricing posts here are the ones that show the arithmetic rather than the conclusion.

Someone should write this up properly, and it should probably not be me.

2 likes 8mo
CL
coldchain_liuTL3Regular25 Nov 2025#23
w.moreau, post #1: Price changes over 2025 and 2026, tabulated and dated — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Documenting an access outcome, dated, because everything in this category expires. As of January 2026, in my region, the position is as described below. I have linked the… Go to post

I would put moderate confidence on the mainstream reading of Price changes and no more. That is not scepticism for its own sake; it is where the sourcing actually stops.

0 likes in reply to #1 8mo
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GDashwoodTL3Regular26 Nov 2025#24

Larger orders shift risk as well as price, because more of your material then comes from one lot.

Written in the hope of being told what I have missed.

27 likes 8mo
LE
logbook_erinTL3Regular28 Nov 2025#25

Answering the question post #21 raises rather than the one it answers.

Answering the Price changes question as asked, then the question I think is meant. As asked: yes, with the qualification below. As meant: it depends on how the first measurement was taken.

5 likes 8mo
AI
a.ilungaTL229 Nov 2025#26

The arithmetic in post #25 is right; the assumption feeding it is the part to check.

On Price changes: the maintained page in the documentation commons covers the general case with citations and a review date, which is more reliable than any reply here including this one.

0 likes 8mo
MM
maintenance_modeTL3Regular1 Dec 2025#27
GDashwood, post #24: Larger orders shift risk as well as price, because more of your material then comes from one lot. Written in the hope of being told what I have missed. Go to post

Useful. I have added it to my own notes with the date on it.

0 likes in reply to #24 8mo
AP
au.pereiraTL22 Dec 2025#28

Price variation between pharmacies: identical prescriptions can cost different amounts at different pharmacies because pharmacies negotiate individually with insurers and manufacturers.

That matches what I was told, which is not the same as knowing it.

20 likes 8mo
LC
l.cabreraTL24 Dec 2025#29

For anyone finding this later: the short answer on Price changes is that it depends on one thing, and the rest of the thread is people identifying which thing.

2 likes 8mo
SF
sterile_fileTL3Regular5 Dec 2025#30
journalclub_wren, post #17: A price well below the rest of the market is a fact rather than a finding, and it is worth noting without concluding from it. Scoping that to what I have actually seen rather than what I have read. Go to post

Narrowing post #29, because the general version has more than one answer.

Price changes is one of those subjects where the general answer and the answer for a specific case diverge, and the thread will go in circles until someone says which one is being asked for.

0 likes in reply to #17 8mo