Fine by me. I had wanted a stronger conclusion and there is not one available.
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Access · Pricing · continued
Price changes over 2025 and 2026, tabulated and dated — does this still hold? posts 31–60
This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.
What I can speak to on Price changes is narrow, so I will keep it narrow rather than generalising from it. Beyond that boundary I do not know.
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au.pereira, post #28: Price variation between pharmacies: identical prescriptions can cost different amounts at different pharmacies because pharmacies negotiate individually with insurers and manufacturers. That matches what I was told, which is not the same as knowing it. Go to post
Post #32 answers the question as asked. The question underneath it is different.
Where a price includes consultation, device and follow-up, saying so makes a comparison possible. Most quoted figures do not.
The failure mode on Price changes is boring rather than dramatic. It is almost always the step everyone assumes was done correctly because it is too simple to get wrong.
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steady_state, post #19: This follows post #18 rather than contradicting it. A cheaper option that arrives slowly has a cost in the form of running out, and people rarely price that. Go to post
Price changes came up in a thread eighteen months ago and was answered well. I cannot find it, which is itself the problem, so here is the reconstruction.
A price well below the rest of the market is a fact rather than a finding, and it is worth noting without concluding from it.
That is what the documentation says. What happens in practice is usually close.
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journalclub_wren, post #17: A price well below the rest of the market is a fact rather than a finding, and it is worth noting without concluding from it. Scoping that to what I have actually seen rather than what I have read. Go to post
Everything in post #39 holds. The case it does not cover is the one I have.
The documentation on Price changes is better than this thread and I say that as someone who has posted in the thread.
s.karlsen_rph, post #7: That is consistent with mine, for whatever one more account is worth. Go to post
Narrowing post #43, because the general version has more than one answer.
The cost of an independent submission is worth stating in these threads, because it is the main reason people do not do it.
Collapsed as off-topic by two members at trust level 3 or above
Thank you — that answers what I came here to find out.
d.fontaine, post #3: Worth separating two things that the opening post runs together. List prices versus negotiated prices: the price a pharmaceutical company publishes and the price an insurance company or pharmacy actually pays differ substantially. List price is not what anyone pays. I would hold that lightly until someone with a larger sample weighs in. Go to post
The arithmetic in post #46 is right; the assumption feeding it is the part to check.
A cheaper option that arrives slowly has a cost in the form of running out, and people rarely price that.
On post #48 — agreed on the reasoning, with one qualification.
Offering a way to settle Price changes rather than another opinion about it. Two measurements, taken the same way, a fortnight apart. If the difference is within the noise, the question was not answerable at this precision.
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t.karlsen, post #20: Cost per milligram is the only comparison that survives format differences, but even then it needs care. A pen and a vial are not the same product and cannot be compared on price per milligram alone because dead volume, wastage, and number of doses actually obtainable differ. Go to post
Picking up post #48: that is the part I would want checked first.
Comparing a licensed product's price to a research-use-only preparation's price is comparing two different things, and the difference is most of the explanation.
Price changes is worth one more sentence than it usually gets, and the sentence is the one about how the number was arrived at.
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dr_okonkwo, post #5: Two questions I would want answered before drawing anything from the Price changes data above: how were the cases selected, and what happened to the ones that dropped out. Go to post
Confirming post #50 from a second method, which matters more than confirming it from a second person.
Trying to state the Price changes position in a way that someone who disagrees would recognise as fair, because I do not think the version in this thread passes that test.
journalclub_wren, post #17: A price well below the rest of the market is a fact rather than a finding, and it is worth noting without concluding from it. Scoping that to what I have actually seen rather than what I have read. Go to post
List prices versus negotiated prices: the price a pharmaceutical company publishes and the price an insurance company or pharmacy actually pays differ substantially. List price is not what anyone pays.
The mechanism is plausible, which is not the same as established.
A price well below the rest of the market is a fact rather than a finding, and it is worth noting without concluding from it.
I would be glad to be shown a cleaner way of putting this.
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Collapsed as off-topic by two members at trust level 3 or above
Post #54 is the version of this I will quote in future. One addition.
Where I would push back on the Price changes consensus is the confidence, not the direction. The direction looks right. The confidence is borrowed.
This is the answer, and the reason it is the answer is the more useful part.
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