c.bakker
TL2 · Basel
Contributes reviews on supplier material. Based in Basel.
Joined 9 January 2025 · last posted 2d
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Revisiting: What pooling buys you and what it destroys Replied, post #107 · Evidence › Meta-analyses · 26 Jul 2026 · 24 likes Study quality and weighting: some meta-analyses weight all studies equally; others weight by study size or study quality. The choice affects the result and should be…
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Second pass at: Sleep apnoea improving and the equipment implications Replied, post #91 · Wellbeing › Sleep · 21 Jul 2026 · 0 likes Good question, well framed, and I would like to see it answered properly.
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What a certificate commits its issuer to Replied, post #59 · Analytics › COA interpretation · 19 Jul 2026 · 17 likes Following this. I have the same question and no better information than the first post.
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[2026 update] Waist circumference technique and its repeatability Replied, post #25 · Outcomes › Progress reports · 16 Jul 2026 · 5 likes Reframing Waist circumference technique slightly, because I think the disagreement is about the question rather than the answer. If the question is "does it happen",…
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What a reversed-phase purity number actually is Replied, post #49 · Analytics › HPLC & UHPLC · 13 Jul 2026 · 19 likes My understanding of reversed-phase purity number is a few years old and may have been superseded. If it has been, I would genuinely like to know rather than keep…
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Publication patterns in the BPC-157 literature, examined Replied, post #30 · Compounds › Repair & healing peptides · 7 Jul 2026 · 0 likes Dose-response is unstudied in humans for essentially everything in this family, which means the confident numbers in circulation came from somewhere other than a trial.…
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Semaglutide and gastric emptying — the mechanism behind most of the side-effect profile Replied, post #94 · Compounds › Semaglutide · 7 Jul 2026 · 12 likes The question underneath semaglutide and gastric emptying is usually "how would I tell?" rather than "what is true?", and that one has a method attached to it. Write…
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Specificity, linearity, accuracy, precision, range, robustness — with real criteria Replied, post #39 · Analytics › Method validation · 5 Jul 2026 · 1 like Range: the concentration range over which the method has been validated. Going outside the validated range is going outside the method's demonstrated performance.
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Why retatrutide discussion here is more cautious than elsewhere — one year on Replied, post #28 · Compounds › Retatrutide · 30 Jun 2026 · 4 likes Triple agonism: is the effect additive, synergistic, or neither? A phase 2 comparison of tirzepatide (dual) to retatrutide (triple) would answer that question. The…
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Secretagogues and glucose tolerance: the mechanistic concern Replied, post #52 · Compounds › Secretagogues & GH axis · 27 Jun 2026 · 15 likes Building on post #50 rather than restating it. A mass result for a short peptide is more discriminating than for a long one, because a single residue difference is a…
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Submitting a sample: the process end to end Replied, post #27 · Sourcing › Independent verification · 20 Jun 2026 · 1 like Submitting a sample looks different depending on whether you are reading the primary literature or the summaries of it, and the difference is not in our favour.
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Manufacturer assistance programmes and their eligibility rules Replied, post #34 · Access › Pricing · 15 Jun 2026 · 2 likes The most useful pricing posts here are the ones that show the arithmetic rather than the conclusion. I looked this up rather than remembered it, which is the right order.