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Evidence · Meta-analyses

Revisiting: What pooling buys you and what it destroys

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Solved by i.grimaldi in post #4
I had written a reply contradicting the opening post and deleted it. Here is what survived. What I want from this pooling buys thread is the list of things that would need to be true for the claim to hold. If we can write that list, we can check it.

Jump to the accepted answer →

JW
journalclub_wrenTL3Regular15 Apr 2026#1

On the subject in the title: Revisiting: What pooling buys you and what it destroys Working notes rather than a conclusion.

Pooling buys — I have the observation and I do not trust my interpretation of it, so I am posting the observation and holding the interpretation back.

Numbers, method and the conditions under which they were collected are below. Interpret them however they warrant.

30 likes 3mo
ZA
z.adeyemiTL218 Apr 2026 · edited#2

Pooling buys is a good example of a question where the honest answer is boring and the interesting answers are unsupported. I would go with boring.

31 likes 3mo
EF
erratum_fileTL3Regular20 Apr 2026#3

Confirming post #2 from a second method, which matters more than confirming it from a second person.

Double extraction with disagreement resolution is standard and is worth checking for, because single extraction errors are common and non-random.

One more caveat and then I will stop qualifying: the sample selected itself.

0 likes 3mo
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i.grimaldiTL2 Solution22 Apr 2026#4

I had written a reply contradicting the opening post and deleted it. Here is what survived.

What I want from this pooling buys thread is the list of things that would need to be true for the claim to hold. If we can write that list, we can check it.

10 likes 3mo
GF
gradient_fileTL2Member23 Apr 2026#5
journalclub_wren, post #1: On the subject in the title: Revisiting: What pooling buys you and what it destroys Working notes rather than a conclusion. Pooling buys — I have the observation and I do not trust my interpretation of it, so I am posting the observation and holding the interpretation back. Numbers, method and the conditions under which they were… Go to post

The arithmetic in post #2 is right; the assumption feeding it is the part to check.

On pooling buys, I would rather understate and be corrected upward than overstate and be quoted. That is a house style here and it is a good one.

22 likes in reply to #1 3mo
CV
ca.vermeulenTL225 Apr 2026#6

Study quality and weighting: some meta-analyses weight all studies equally; others weight by study size or study quality. The choice affects the result and should be stated and justified.

The variance between people here is larger than the effect being discussed.

0 likes 3mo
EL
endpoint_lineTL3Regular26 Apr 2026#7

Nothing to add on the substance. Thank you for taking the question at face value.

1 like 3mo
SK
s.kravchenkoTL228 Apr 2026#8

Where I part company with post #4, and it is a narrow parting.

Double extraction with disagreement resolution is standard and is worth checking for, because single extraction errors are common and non-random.

6 likes 3mo
KB
k.brandl_deTL3Translator · DE29 Apr 2026 · edited#9

Narrowing post #6, because the general version has more than one answer.

Filing a mild objection to the consensus on pooling buys. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit.

30 likes 3mo
VB
v.bruunTL230 Apr 2026#10

Everything in post #8 holds. The case it does not cover is the one I have.

Study quality and weighting: some meta-analyses weight all studies equally; others weight by study size or study quality. The choice affects the result and should be stated and justified.

A weak preference rather than a position.

0 likes 3mo
SD
s.duarteTL22 May 2026#11

Adding a null result on pooling buys. I looked, carefully, and found nothing, and null results deserve posting precisely because they never are.

15 likes 3mo
MY
m.yilmazTL23 May 2026#12

Double extraction with disagreement resolution is standard and is worth checking for, because single extraction errors are common and non-random.

That is all the detail I have. Someone else will have more.

5 likes 3mo
JD
j.dahlbergTL24 May 2026#13
endpoint_line, post #7: Nothing to add on the substance. Thank you for taking the question at face value. Go to post

What I would tell a new member reading about pooling buys for the first time: the confident posts are not the reliable ones, and the reliable ones are longer.

0 likes in reply to #7 3mo
VB
v.bhattacharyaTL25 May 2026#14

This follows post #11 rather than contradicting it.

The strongest argument against my own position on pooling buys, stated as well as I can state it, since nobody else has yet.

30 likes 3mo
AK
a.kowalskiTL26 May 2026#15

Study quality and weighting: some meta-analyses weight all studies equally; others weight by study size or study quality. The choice affects the result and should be stated and justified.

Happy to expand any of that if it is the useful part.

10 likes 3mo
TW
t.wojcikTL28 May 2026 · edited#16

An update on my earlier pooling buys post: the pattern held for another six weeks and then stopped, which I did not predict and cannot explain.

3 likes 3mo
FA
f.amankwahTL29 May 2026#17
s.duarte, post #11: Adding a null result on pooling buys. I looked, carefully, and found nothing, and null results deserve posting precisely because they never are. Go to post

On post #15 — agreed on the reasoning, with one qualification.

Pooling buys sits at the boundary between what this community can usefully discuss and what it cannot, and I think it falls on the discussable side, narrowly.

0 likes in reply to #11 3mo
EP
e.piresTL210 May 2026#18
s.kravchenko, post #8: Where I part company with post #4, and it is a narrow parting. Double extraction with disagreement resolution is standard and is worth checking for, because single extraction errors are common and non-random. Go to post

Acknowledging rather than arguing. The reasoning holds as far as I can follow it.

22 likes in reply to #8 3mo
CO
c.ostergaardTL211 May 2026#19

Answering the question post #15 raises rather than the one it answers.

Double extraction with disagreement resolution is standard and is worth checking for, because single extraction errors are common and non-random.

Stating my assumptions rather than smuggling them in.

29 likes 3mo
HS
hana.satoTL4 Moderator12 May 2026#20
j.dahlberg, post #13: What I would tell a new member reading about pooling buys for the first time: the confident posts are not the reliable ones, and the reliable ones are longer. Go to post

The arithmetic in post #19 is right; the assumption feeding it is the part to check.

On pooling buys, the part that usually goes wrong is that the question is asked as though it has one answer. It has a range, and the width of the range is the interesting bit.

If you can post the two or three numbers you are working from, several people here will check the arithmetic rather than argue about the conclusion.

14 likes in reply to #13 3mo
NN
n.nakamuraTL213 May 2026#21

Whatever the answer on pooling buys turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, invite the correction.

0 likes 3mo
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a.salcedoTL3Regular14 May 2026 · edited#22

Study quality and weighting: some meta-analyses weight all studies equally; others weight by study size or study quality. The choice affects the result and should be stated and justified.

The disagreement above is smaller than it looks once the terms are fixed.

4 likes 2mo
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a.sorensenTL215 May 2026#23

I came in to disagree and I am leaving without a disagreement.

13 likes 2mo
EO
e.okaforTL216 May 2026#24
a.kowalski, post #15: Study quality and weighting: some meta-analyses weight all studies equally; others weight by study size or study quality. The choice affects the result and should be stated and justified. Happy to expand any of that if it is the useful part. Go to post

Answering the question post #22 raises rather than the one it answers.

The version of pooling buys that I was taught turned out to be a teaching simplification. Useful, and not true in the way I had assumed it was.

27 likes in reply to #15 2mo
LT
l.trevinoTL217 May 2026#25
n.nakamura, post #21: Whatever the answer on pooling buys turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, invite the correction. Go to post

Adding a small correction to the pooling buys summary above rather than a disagreement with it. The substance holds; one of the figures is out by a factor that matters.

2 likes in reply to #21 2mo
SR
s.rasmussenTL218 May 2026#26

Double extraction with disagreement resolution is standard and is worth checking for, because single extraction errors are common and non-random.

The conclusion is tentative; the arithmetic underneath it is not.

8 likes 2mo
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f.wojcikTL219 May 2026#27

Adding the measurement that post #24 says would settle it.

One caution on pooling buys: everything above assumes the underlying documentation is what it claims to be. That assumption is doing real work and is rarely stated.

19 likes 2mo
FF
f.fonsecaTL220 May 2026#28
a.kowalski, post #15: Study quality and weighting: some meta-analyses weight all studies equally; others weight by study size or study quality. The choice affects the result and should be stated and justified. Happy to expand any of that if it is the useful part. Go to post

Post #26 describes the usual case. This is about the unusual one.

Individual participant data pooling is a much stronger design than aggregate pooling and is rare because it requires cooperation rather than a search.

0 likes in reply to #15 2mo
MN
m.ndiayeTL221 May 2026 · edited#29

Taking post #28 at face value and following it one step further.

Double extraction with disagreement resolution is standard and is worth checking for, because single extraction errors are common and non-random.

4 likes 2mo
HK
h.kjeldsenTL1Member22 May 2026#30

A definition problem is doing most of the work in this pooling buys discussion. Once the term is pinned down I suspect the disagreement mostly goes away and what is left is small.

13 likes 2mo