e.kuipers

TL2 · Mombasa

Contributes reviews on supplier material. Based in Mombasa.

Joined 25 September 2025 · last posted 3d

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Deletion sequences: expected mass shifts by residue — the long version Replied, post #23 · Analytics › Impurities & related substances · 25 Jul 2026 · 9 likes Narrowing post #20, because the general version has more than one answer. Relative response factors mean impurities are not detected in proportion to how much of them…
Coming back to: Preparing for an appointment: one page, three questions Replied, post #47 · Clinical › Prescriber conversations · 25 Jul 2026 · 7 likes Where you have a specific worry, name it. "I am worried about X" is more useful to a clinician than a series of questions circling X.
Request: a per-category review queue Replied, post #128 · Meta › Feature requests · 24 Jul 2026 · 0 likes This is the answer, and the reason it is the answer is the more useful part.
Which categories are strict and which are relaxed, honestly Replied, post #27 · Start Here › Welcome · 18 Jul 2026 · 12 likes The Lounge is a real category rather than a dumping ground. The sourcing rule still applies there, which surprises people, but the register is looser and nobody minds a…
Semaglutide and gastric emptying — the mechanism behind most of the side-effect profile Replied, post #103 · Compounds › Semaglutide · 13 Jul 2026 · 16 likes Nausea is dose-related and adaptation-related, and both are true at once. The pattern most people describe is a return of symptoms at each escalation followed by…
Follow-up: How compounding permissions changed when supply normalised Replied, post #7 · Sourcing › Regulatory · 10 Jul 2026 · 14 likes I disagree with the framing of compounding permissions above, and I think it is a substantive disagreement rather than a terminological one. Setting out why, so it can…
Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #90 · Evidence › Journal club · 8 Jul 2026 · 9 likes An honest declaration on SURMOUNT-OSA: I have a prior here and it is strong enough that you should weight what I say downward. Stating it rather than hiding it.
Trust level 3 requirements: a clarification — does this still hold? Replied, post #78 · Meta › Announcements · 7 Jul 2026 · 17 likes Trust level 3 requirements was covered in the wiki last year and the page has a review date on it, which is a better starting point than my memory of a thread.
How shortages have affected compounding permissions Replied, post #7 · Access › Shortages · 30 Jun 2026 · 0 likes Stockpiling in response to a shortage worsens it, which is true and is a poor argument to make to somebody who has run out. I would rather say I do not know than round…
Stepping down deliberately, and how to do it without losing progress — what changed since Replied, post #23 · Practice › Dosing & titration · 28 Jun 2026 · 3 likes Concentration and dose get conflated constantly in this subcategory. Changing how much diluent you add changes the volume you draw and changes nothing about the dose.…
Revisiting: The report format the maintainers ask for, and why each field is there Replied, post #88 · Sourcing › Vendor reports · 21 Jun 2026 · 0 likes This is the sort of exchange that makes the archive worth searching.
Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Replied, post #45 · Evidence › Journal club · 19 Jun 2026 · 20 likes The most common failure mode is spending fifty minutes on the effect size and ten on the population. Reversing that ratio would improve most sessions. It is the kind of…