r.torrence
TL2 Member · Nijmegen, NL
Keeps a personal log and shares the numbers when they are relevant, with the measurement caveats attached.
Joined 16 August 2025 · last posted 3d
68Posts here
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Semaglutide formulation: what is in the licensed product besides the peptide Replied, post #35 · Compounds › Semaglutide · 25 Jul 2026 · 13 likes Semaglutide formulation looks different depending on whether you are reading the primary literature or the summaries of it, and the difference is not in our favour.
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GIP receptor agonism and the argument about direction — does this still hold? Replied, post #14 · Pharmacology › Receptor biology · 25 Jul 2026 · 4 likes Amylin receptor signalling: amylin promotes satiety and slows gastric emptying through a receptor distinct from GLP-1. The hypothesis behind combination therapy is two…
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Reading order for a first week here, and what to skip until later — what changed since Replied, post #72 · Start Here › Welcome · 22 Jul 2026 · 25 likes That matches what I have seen, for whatever a single anecdote is worth.
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Documenting a supplier's response to a discrepancy Replied, post #39 · Sourcing › Vendor reports · 15 Jul 2026 · 3 likes Post #37 and I disagree about the size of the effect, not about the direction. Reports of ordinary results are more valuable than reports of remarkable ones, precisely…
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Stepping down deliberately, and how to do it without losing progress — what changed since Replied, post #28 · Practice › Dosing & titration · 30 Jun 2026 · 16 likes Where I part company with post #24, and it is a narrow parting. Concentration and dose get conflated constantly in this subcategory. Changing how much diluent you add…
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Why the timeline is on the right and not the left — what changed since Replied, post #64 · Meta › Site feedback · 29 Jun 2026 · 6 likes If you are new and reading this thread for the answer to timeline: the answer is conditional, the conditions are in the third reply, and the rest of the thread is worth…
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GLP-1 receptor distribution: central and peripheral Replied, post #78 · Pharmacology › Receptor biology · 27 Jun 2026 · 0 likes Adding a note of thanks rather than an opinion. I did not know most of that.
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Secretagogues and glucose tolerance: the mechanistic concern Replied, post #41 · Compounds › Secretagogues & GH axis · 19 Jun 2026 · 0 likes This follows post #38 rather than contradicting it. Summarising the secretagogues and glucose tolerance thread so far, since it is long and the answer is buried: the…
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Submitting a sample: the process end to end Replied, post #12 · Sourcing › Independent verification · 11 Jun 2026 · 12 likes Careful with the language on submitting a sample. "Not detected" and "not present" are different findings and the first is a statement about the method.
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Angle of injection and whether 90 degrees is always right — the long version Replied, post #20 · Practice › Administration · 9 Jun 2026 · 23 likes This is the first time the answer has come with its own limits attached. Appreciated.
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Official shortage notices and what they authorise Replied, post #93 · Access › Shortages · 7 Jun 2026 · 1 like Shortages end and the notices are updated. Checking the current notice takes a minute and is more reliable than a thread from March. The literature is thinner on this…
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A certificate whose chromatogram axes do not match its stated method — one year on Replied, post #95 · Sourcing › Red flags · 6 Jun 2026 · 0 likes Reporting something here requires the batch, the date, the method and the document, which is exactly what makes the reports worth reading two years later.