A genuinely late dose: what the labelling says and what people do — what changed since
Post #3 is right about the mechanism and I think understates the practical bit.
Injecting slowly is worth doing for volume rather than for chemistry. Larger volumes delivered quickly are the ones people report as uncomfortable.
I would not lead a decision with this, but I would not ignore it either.
Subcutaneous injection into abdominal tissue, thigh or upper arm is what the licensed labelling in this class describes, and the published comparisons found the differences in exposure between those sites small.
A request rather than an answer: could whoever has the primary source for genuinely late dose post it? I have seen the claim three times this month and each version had lost a qualifier.
Post #10 put the caveat in the right place and I want to underline it.
A site rotation scheme that actually works: abdomen, outer thigh, back of arm, outer hip. Rotate through them in order, move a minimum 2 cm between consecutive sites, note the site with each dose. If a local reaction appears you have the history. If you rotate properly you will not get lipohypertrophy from overuse of one area.
I have changed my mind on this once already, so take it as current rather than settled.
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- A site rotation scheme that is easy enough to actually followPractice › Administration · 125 replies
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