The Peptide CommonsEst. May 2024
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Tags · Practice

dead volume

Residual liquid in hub and needle, and the dose it silently removes.

49 topics 13 solved Group: Practice

Related in this group: reconstitution · bacteriostatic water · sterile water · concentration maths · syringe units · titration · dose reduction · missed dose · injection site rotation · needle gauge & length · subcutaneous injection · storage

49 topics · page 1 of 2

TopicParticipantsRepliesViewsActivity
Reading a syringe in poor light, and how to avoid needing to
Reading a syringe in poor light, and how to avoid needing to Writing it up because I had to work it out twice and would rather nobody else did. The question about reading a syringe that I actually want…
CRRMTD 2 22k just now
Revisiting: Drawing from a pen cartridge with a syringe: how the risk profile changes
Revisiting: Drawing from a pen cartridge with a syringe: how the risk profile changes Writing it up because I had to work it out twice and would rather nobody else did. Question about a metering device rather…
IDRSNG 2 18k 6h
Fixed versus detachable needles: the trade-offs — does this still hold?
Fixed versus detachable needles: the trade-offs — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Working notes on Fixed versus detachable…
CVFHKRZSUC+8 12 39k 15h
Why a pen's dose steps are fixed and what that costs you
The question in the title: Why a pen's dose steps are fixed and what that costs you I will give what I have already checked below so nobody repeats it. A question about a device rather than about a compound,…
EMBVIABDNK 4 2.5k 23h
Reading U-100 graduations, with a conversion table
Posting this under the heading it deserves: Reading U-100 graduations, with a conversion table Everything below is what sits behind that. A question about reading U-100 graduations that I think has a definite…
YERDKFKVKP+35 41 2k 1d
Coming back to: Why I now write the concentration on the vial in marker
The question in the title: Why I now write the concentration on the vial in marker I will give what I have already checked below so nobody repeats it. Writing this out with the numbers in it, because…
EBJTGCHNS+8 12 4.3k 1d
How much of the diluent volume the powder itself displaces
Asking directly, because I could not find a straight answer: How much of the diluent volume the powder itself displaces Writing this out with the numbers in it, because "roughly" is how these go wrong. Vial:…
CCFPHI 2 1.8k 1d
Priming a pen and whether the primed volume is wasted
Priming a pen and whether the primed volume is wasted Writing it up because I had to work it out twice and would rather nobody else did. I have spent a fortnight trying to pin priming a pen down and I want to…
ANGHCHFAFI+19 23 1.3k 2d
0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters
0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters — setting out what I have, and where I think it stops being reliable. A follow-up question about 0.3 ml versus 0.5 ml that I did not know to ask…
KABVRCTAK+104 114 6k 6d
Reading a syringe in poor light, and how to avoid needing to — what changed since
Posting this under the heading it deserves: Reading a syringe in poor light, and how to avoid needing to — what changed since Everything below is what sits behind that. What changes if the standard account of…
FSCILDCDHA+3 7 27k 27d
[2026 update] A vial that will not fully dissolve: what to check and in what order
Posting this under the heading it deserves: A vial that will not fully dissolve: what to check and in what order Everything below is what sits behind that. Practical question with the units stated, because I…
HBASNKITNC+114 128 20k 1mo
About the Syringes & needles category
Insulin syringe graduations, dead volume, gauge and length selection, and reading units correctly. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded…
DOOBAFMICB 4 45k 1mo
Reading U-100 graduations, with a conversion table — what changed since
Reading U-100 graduations, with a conversion table — what changed since Writing it up because I had to work it out twice and would rather nobody else did. What changes if the standard account of Reading U-100…
MBPOCO 2 10k 2mo
[2026 update] 0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters
On the subject in the title: 0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters Working notes rather than a conclusion. A follow-up question about 0.3 ml versus 0.5 ml that I did not know to ask the…
MKBPNHAAV+108 124 27k 2mo
Foaming during reconstitution and whether it matters — the long version
Foaming during reconstitution and whether it matters — the long version — setting out what I have, and where I think it stops being reliable. A narrow question about Foaming during reconstitution,…
BFMDRMNGMM+100 117 6k 3mo
Converting between mg/mL and units per dose, both directions — the long version
Converting between mg/mL and units per dose, both directions — the long version Writing it up because I had to work it out twice and would rather nobody else did. Practical question with the units stated,…
COZAGFSKW+110 132 1.7k 3mo
Reading U-100 graduations, with a conversion table — one year on
Reading U-100 graduations, with a conversion table — one year on Writing it up because I had to work it out twice and would rather nobody else did. I would like to disagree carefully with the settled view on…
AICDSBGHNN+3 7 662 4mo
About the Pens & autoinjectors category
Pen mechanics, dose counters, priming, and what happens when a pen is used off its label. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its…
TVHSJASSIW+1 5 92 5mo
Dead volume across syringe and needle combinations
On the subject in the title: Dead volume across syringe and needle combinations Working notes rather than a conclusion. Something about dead volume across syringe does not reconcile and I would like a second…
ECCOFWWNJF+72 80 28k 5mo
Filter needles: when they help and what they cost you
On the subject in the title: Filter needles: when they help and what they cost you Working notes rather than a conclusion. Trying to work out what would count as evidence on filter needles, before collecting…
FWSFECRMTT+45 50 19k 5mo
Coming back to: Pen dose counters: what a click does and does not guarantee
Pen dose counters: what a click does and does not guarantee — setting out what I have, and where I think it stops being reliable. Reading back through what has been written here about Pen dose counters, three…
GLEAICLPK 4 105 5mo
Coming back to: Reconstitution volumes that produce round numbers, tabulated
On the subject in the title: Reconstitution volumes that produce round numbers, tabulated Working notes rather than a conclusion. Writing this out with the numbers in it, because "roughly" is how these go…
CDMNC 2 24k 6mo
A pen that felt like it delivered nothing: diagnosing it afterwards
On the subject in the title: A pen that felt like it delivered nothing: diagnosing it afterwards Working notes rather than a conclusion. Question about a metering device rather than about a syringe, because…
AZFWDSRFOO+35 39 584 6mo
Pen mechanics when the cartridge is nearly empty — does this still hold?
Asking directly, because I could not find a straight answer: Pen mechanics when the cartridge is nearly empty — does this still hold? Pen mechanics — I have the observation and I do not trust my…
YASKJNAKRJ+37 47 61k 6mo
Why "add 2 mL" is not an instruction
The question in the title: Why "add 2 mL" is not an instruction I will give what I have already checked below so nobody repeats it. Practical question with the units stated, because I have seen how quickly…
MLBAIKKN+23 27 3.5k 6mo
Follow-up: The decimal-point error, and the habit that catches it
On the subject in the title: The decimal-point error, and the habit that catches it Working notes rather than a conclusion. A follow-up question about decimal-point error that I did not know to ask the first…
VKAMCILDCD+118 131 50k 7mo
Coming back to: Over-dilution: when your dose falls below one readable graduation
Over-dilution: when your dose falls below one readable graduation Writing it up because I had to work it out twice and would rather nobody else did. I have read the maintained page on this and I still have a…
MLFAPICOTW+90 97 1.1k 7mo
Gauge and length selection for subcutaneous injection
Gauge and length selection for subcutaneous injection Writing it up because I had to work it out twice and would rather nobody else did. A follow-up question about gauge and length selection that I did not…
NVARNSOBHM+50 55 1.3k 8mo
Needle changes between doses on a reusable pen
Posting this under the heading it deserves: Needle changes between doses on a reusable pen Everything below is what sits behind that. The question about needle changes between doses that I actually want…
KMKKLSKAW+34 38 1.5k 10mo
A ten-fold dose error caught before injection
A ten-fold dose error caught before injection — setting out what I have, and where I think it stops being reliable. Trying to work out what would count as evidence on ten-fold dose error caught, before…
CBCNZARAK+95 103 26k 10mo