Tags · Practice

storage

Refrigeration, room temperature limits and light protection.

63 topics 14 solved Group: Practice

63 topics · page 1 of 3

Topic	Participants	Replies	Views	Activity
Revisiting: Drawing from a pen cartridge with a syringe: how the risk profile changes Devices › Pens & autoinjectors dead volume missed dose storage subcutaneous injection Revisiting: Drawing from a pen cartridge with a syringe: how the risk profile changes Writing it up because I had to work it out twice and would rather nobody else did. Question about a metering device rather…		2	18k	6h
Coming back to: Solubility limits and what a cloudy solution is telling you Pharmacology › Formulation chemistry sterile water cloudy or discoloured solution storage counter-ion content On the subject in the title: Solubility limits and what a cloudy solution is telling you Working notes rather than a conclusion. Reading back through what has been written here about Solubility limits, three…	+38	43	29k	13h
A fridge failure and how I assessed the contents afterwards Devices › Cold chain cold chain storage temperature excursion A fridge failure and how I assessed the contents afterwards Writing it up because I had to work it out twice and would rather nobody else did. The question about fridge failure that I actually want answered…	+14	18	46k	17h
Solubility limits and what a cloudy solution is telling you Pharmacology › Formulation chemistry cloudy or discoloured solution storage counter-ion content Solubility limits and what a cloudy solution is telling you — setting out what I have, and where I think it stops being reliable. The question about solubility limits that I actually want answered is the…	+11	15	34k	20h
Why a pen's dose steps are fixed and what that costs you Devices › Pens & autoinjectors dead volume storage subcutaneous injection missed dose Solved The question in the title: Why a pen's dose steps are fixed and what that costs you I will give what I have already checked below so nobody repeats it. A question about a device rather than about a compound,…		4	2.5k	23h
Coming back to: Light exposure: how much protection is proportionate? Practice › Storage & stability temperature excursion cold chain freeze-thaw cloudy or discoloured solution Asking directly, because I could not find a straight answer: Light exposure: how much protection is proportionate? Reading back through what has been written here about Light exposure, three questions come up…	+5	10	13k	2d
Priming a pen and whether the primed volume is wasted Devices › Pens & autoinjectors storage missed dose dead volume Solved Wiki Priming a pen and whether the primed volume is wasted Writing it up because I had to work it out twice and would rather nobody else did. I have spent a fortnight trying to pin priming a pen down and I want to…	+19	23	1.3k	2d
Preservatives: function, testing, and limits — one year on Pharmacology › Formulation chemistry sterile water cloudy or discoloured solution storage bacteriostatic water Wiki On the subject in the title: Preservatives: function, testing, and limits — one year on Working notes rather than a conclusion. Asking about Preservatives directly, because I have read four threads on it and…	+28	32	437	8d
[2026 update] Does a peptide degrade silently, with no visual change? Practice › Storage & stability temperature excursion storage freeze-thaw cold chain Does a peptide degrade silently, with no visual change? — that is the question, and I have not found it answered plainly anywhere I have looked. I have read the maintained page on this and I still have a gap,…	+82	86	24k	15d
Second pass at: Temperature logging at home: what is worth the effort Practice › Storage & stability temperature excursion cloudy or discoloured solution freeze-thaw cold chain Posting this under the heading it deserves: Second pass at: Temperature logging at home: what is worth the effort Everything below is what sits behind that. Posting a small dataset on Temperature logging. It…	+4	8	29k	1mo
Transporting a vial for a weekend away — a second dataset Practice › Storage & stability storage cold chain beyond-use date Transporting a vial for a weekend away — a second dataset Writing it up because I had to work it out twice and would rather nobody else did. Posting a small dataset on Transporting a vial. It is mine, it is…	+74	84	5.1k	1mo
[2026 update] Storing lyophilised material long term: what governs the shelf life Practice › Storage & stability beyond-use date freeze-thaw cold chain cloudy or discoloured solution Storing lyophilised material long term: what governs the shelf life — setting out what I have, and where I think it stops being reliable. Two things I would like separated before anyone answers on Storing…	+122	133	35k	1mo
A reconstituted vial's beyond-use date and the reasoning behind common figures Practice › Storage & stability temperature excursion storage freeze-thaw Posting this under the heading it deserves: A reconstituted vial's beyond-use date and the reasoning behind common figures Everything below is what sits behind that. I have read the maintained page on this…	+125	129	45k	2mo
Revisiting: Mean kinetic temperature explained without the mathematics Practice › Storage & stability storage cold chain temperature excursion cloudy or discoloured solution Solved Revisiting: Mean kinetic temperature explained without the mathematics Writing it up because I had to work it out twice and would rather nobody else did. A methods question rather than a substantive one,…	+67	75	909	2mo
Light exposure: how much protection is proportionate? Practice › Storage & stability beyond-use date freeze-thaw cold chain cloudy or discoloured solution The question in the title: Light exposure: how much protection is proportionate? I will give what I have already checked below so nobody repeats it. Trying to establish the boundary conditions on light…		2	59	3mo
[2026 update] Buffers, pH and why a formulation is a formulation Pharmacology › Formulation chemistry counter-ion content storage bacteriostatic water cloudy or discoloured solution Posting this under the heading it deserves: Buffers, pH and why a formulation is a formulation Everything below is what sits behind that. A formulation question rather than a pharmacological one, though the…		2	773	3mo
Second pass at: Adsorptive losses at low concentration, and why dilute solutions are fragile Practice › Storage & stability beyond-use date freeze-thaw cloudy or discoloured solution storage Closed On the subject in the title: Second pass at: Adsorptive losses at low concentration, and why dilute solutions are fragile Working notes rather than a conclusion. The question about Adsorptive losses that I…	+77	87	58k	4mo
About the Storage & stability category Practice › Storage & stability storage temperature excursion cold chain Pinned Wiki Refrigeration, excursions, light exposure, freeze-thaw, beyond-use dating, and what published stability data actually covers. This post is a community wiki: any member at trust level 3 or above can edit it,…		4	57k	4mo
Adsorptive losses at low concentration, and why dilute solutions are fragile Practice › Storage & stability storage cold chain beyond-use date Adsorptive losses at low concentration, and why dilute solutions are fragile — setting out what I have, and where I think it stops being reliable. Collecting what is known about adsorptive losses in one…	+16	20	1.7k	4mo
About the Pens & autoinjectors category Devices › Pens & autoinjectors dead volume missed dose storage Pinned Wiki Pen mechanics, dose counters, priming, and what happens when a pen is used off its label. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its…	+1	5	92	5mo
Storing in the door of the fridge is worse than you think Practice › Storage & stability cold chain beyond-use date storage freeze-thaw Solved Storing in the door of the fridge is worse than you think Writing it up because I had to work it out twice and would rather nobody else did. Asking about the failure mode rather than the procedure, because…		2	8.3k	5mo
Coming back to: Pen dose counters: what a click does and does not guarantee Devices › Pens & autoinjectors storage subcutaneous injection dead volume Pen dose counters: what a click does and does not guarantee — setting out what I have, and where I think it stops being reliable. Reading back through what has been written here about Pen dose counters, three…		4	105	5mo
Temperature loggers worth the money — the long version Devices › Cold chain storage freeze-thaw temperature excursion Closed On the subject in the title: Temperature loggers worth the money — the long version Working notes rather than a conclusion. A narrow question about Temperature loggers worth the money, deliberately narrow,…	+110	127	48k	6mo
Lyophilisation and why the cake looks the way it does Pharmacology › Formulation chemistry sterile water bacteriostatic water storage cloudy or discoloured solution Posting this under the heading it deserves: Lyophilisation and why the cake looks the way it does Everything below is what sits behind that. I was wrong about lyophilisation in a thread last spring and I…	+33	37	60k	6mo
A pen that felt like it delivered nothing: diagnosing it afterwards Devices › Pens & autoinjectors storage subcutaneous injection missed dose dead volume Solved On the subject in the title: A pen that felt like it delivered nothing: diagnosing it afterwards Working notes rather than a conclusion. Question about a metering device rather than about a syringe, because…	+35	39	584	6mo
Pen mechanics when the cartridge is nearly empty — does this still hold? Devices › Pens & autoinjectors storage subcutaneous injection missed dose dead volume Asking directly, because I could not find a straight answer: Pen mechanics when the cartridge is nearly empty — does this still hold? Pen mechanics — I have the observation and I do not trust my…	+37	47	61k	6mo
What published stability data actually covers, and what it does not — what changed since Practice › Storage & stability freeze-thaw storage temperature excursion cloudy or discoloured solution Solved What published stability data actually covers, and what it does not — what changed since — that is the question, and I have not found it answered plainly anywhere I have looked. What changes if the standard…		3	43k	6mo
Temperature logging at home: what is worth the effort Practice › Storage & stability storage beyond-use date cloudy or discoloured solution temperature excursion Temperature logging at home: what is worth the effort — setting out what I have, and where I think it stops being reliable. An honest uncertainty about temperature logging rather than a disguised assertion. I…		2	6.3k	7mo
Airline travel with a temperature-sensitive injectable Devices › Cold chain freeze-thaw cold chain temperature excursion storage Posting this under the heading it deserves: Airline travel with a temperature-sensitive injectable Everything below is what sits behind that. Airline travel: setting out the arithmetic in full, because I have…	+19	23	4.9k	7mo
Second pass at: A reconstituted vial's beyond-use date and the reasoning behind common figures Practice › Storage & stability beyond-use date cold chain temperature excursion freeze-thaw Solved Second pass at: A reconstituted vial's beyond-use date and the reasoning behind common figures Writing it up because I had to work it out twice and would rather nobody else did. Something changed and I would…	+4	8	20k	8mo

Sponsored Janoshik Analytical — independent third-party testingHPLC purity and mass-spectrometric identity on submitted samples, reported with the method stated. The laboratory most often cited in this community’s verification records.Independent testing → Sponsored GL Biochem (Shanghai) Ltd. — synthesis, directFounded 1998. ISO 9001 and cGMP certified, over 1,500 staff and 200-plus patents. Custom peptide synthesis and amino acid derivatives, with a batch certificate on every order.Custom synthesis →