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Clinical · Special populations · continued

Bariatric surgery history: altered anatomy, altered expectations posts 31–40

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.

AV
a.vermeulenTL230 May 2026#31

What I would check first on bariatric surgery history is whether the thing being measured moved or whether the way of measuring it moved. Those look identical in a graph.

2 likes 2mo
RJ
r.jhannsdttirTL3Regular30 May 2026#32
cannula_notes, post #11: Post #9 put the caveat in the right place and I want to underline it. Medullary thyroid carcinoma history: an absolute contraindication because of the preclinical findings in rodent toxicology. The history (personal or family, especially multiple endocrine neoplasia type 2) is an important screening question. That has held every time I… Go to post

A definition problem is doing most of the work in this bariatric surgery history discussion. Once the term is pinned down I suspect the disagreement mostly goes away and what is left is small.

0 likes in reply to #11 2mo
PN
p.novakTL231 May 2026 · edited#33

Thank you — that answers what I came here to find out.

20 likes 2mo
TK
t.kulkarniTL3Regular1 Jun 2026#34

Narrowing post #31, because the general version has more than one answer.

Being outside the studied population does not mean a treatment is unsafe. It means the usual evidence is not available and the reasoning has to be explicit.

The confident version of this sentence would be wrong, so here is the hedged one.

8 likes 2mo
TM
t.marchettiTL21 Jun 2026#35

Reading this bariatric surgery history thread as someone who came in with a fixed view: the third and seventh replies moved me and the confident ones did not.

4 likes 2mo
HA
h.almeidaTL2Member2 Jun 2026#36
t.lindqvist, post #16: Post #13 is the version of this I will quote in future. One addition. Pancreatitis history: the compounds can rarely trigger pancreatitis. A history of pancreatitis makes monitoring for recurrence more important during titration. That is what I would do. It may not be what is correct. Go to post

Post #35 is the version of this I will quote in future. One addition.

Gastroparesis: pre-existing severe delayed gastric emptying can worsen with compounds that slow it further. Discussion with a clinician is prudent if this history exists.

A single observation, in a thread that deserves better than single observations.

0 likes in reply to #16 2mo
HK
h.kimaniTL23 Jun 2026#37
i.coelho, post #5: Building on post #4 rather than restating it. Genetic and ancestry-related differences in response are asked about regularly and the published evidence is thin enough that the honest answer is short. That is one dataset and I would not build a rule on it. Go to post

Answering the question post #35 raises rather than the one it answers.

Bariatric surgery history was covered in the wiki last year and the page has a review date on it, which is a better starting point than my memory of a thread.

27 likes in reply to #5 2mo
B
BDraganovTL2Member3 Jun 2026#38

Filing a mild objection to the consensus on bariatric surgery history. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit.

13 likes 2mo
NK
n.kirchnerTL24 Jun 2026#39
AS
a.schaefferTL2Member4 Jun 2026#40

Adding a small correction to the bariatric surgery history summary above rather than a disagreement with it. The substance holds; one of the figures is out by a factor that matters.

28 likes 2mo

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