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Clinical · Bloodwork · continued

Building a sensible monitoring schedule with your prescriber posts 91–109

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

BO
b.oseiTL222 Dec 2024#91
diluent_watch, post #10: Taking post #7 at face value and following it one step further. Repeat before acting is standard practice for an isolated abnormal result on most analytes, and it is standard for a reason. I would put a moderate confidence on that and no more. Go to post

An honest declaration on building a sensible monitoring schedule: I have a prior here and it is strong enough that you should weight what I say downward. Stating it rather than hiding it.

0 likes in reply to #10 19mo
AR
a.reyesTL4 Admin22 Dec 2024#92

Post #91 put the caveat in the right place and I want to underline it.

Building a sensible monitoring schedule sits at the boundary between what this community can usefully discuss and what it cannot, and I think it falls on the discussable side, narrowly.

2 likes 19mo
BD
b.demirTL222 Dec 2024#93

The arithmetic in post #92 is right; the assumption feeding it is the part to check.

A trend needs at least three points to be a trend. Two points are a line and a line through noise is still a line.

9 likes 19mo
SB
s.bruunTL222 Dec 2024#94

Having read the whole building a sensible monitoring schedule thread before replying: the question in the first post has not actually been answered yet, and three of us have answered a nearby one instead.

21 likes 19mo
RS
r.serranoTL222 Dec 2024#95
s.grimaldi, post #1: Building a sensible monitoring schedule with your prescriber — setting out what I have, and where I think it stops being reliable. Building a sensible monitoring schedule — I have the observation and I do not trust my interpretation of it, so I am posting the observation and holding the interpretation back. Numbers, method and the… Go to post

Time of day: some biomarkers vary across the day. Cortisol in the morning differs from cortisol in the evening. Comparing results from different times of day is comparing things that are not the same.

Stating my assumptions rather than smuggling them in.

0 likes in reply to #1 19mo
MH
ms_hollowayTL4Mass spectrometrist22 Dec 2024#96

Distinguishing three things in the building a sensible monitoring schedule discussion that keep getting used interchangeably: the observation, the proposed mechanism, and the recommendation that gets attached to both.

5 likes 19mo
KD
k.dahlbergTL222 Dec 2024#97

Understood. Thank you for being specific about the limits of it.

14 likes 19mo
OB
owen.bradyTL4 Moderator22 Dec 2024#98
j.erdogan, post #76: Building a sensible monitoring schedule is well covered in the tag pages, and the older discussions are better than the recent ones because they were argued out properly. Worth twenty minutes before adding to this one. Go to post

Everything in post #94 holds. The case it does not cover is the one I have.

What I would tell a new member reading about building a sensible monitoring schedule for the first time: the confident posts are not the reliable ones, and the reliable ones are longer.

29 likes in reply to #76 19mo
CD
cannula_driftTL3Regular22 Dec 2024 · edited#99
peak_purity, post #31: Confirming post #30 from a second method, which matters more than confirming it from a second person. For anyone finding this later: the short answer on building a sensible monitoring schedule is that it depends on one thing, and the rest of the thread is people identifying which thing. Go to post

Confirming post #96 from a second method, which matters more than confirming it from a second person.

Glycaemic markers integrate over different periods. A point glucose and a longer-term marker disagreeing is not a contradiction; it is two different questions.

Not a conclusion. A place to stand while looking for one.

30 likes in reply to #31 19mo
HA
h.amankwahTL223 Dec 2024#100

A trend needs at least three points to be a trend. Two points are a line and a line through noise is still a line.

Worth saying I have only my own numbers here, and n is small.

0 likes 19mo
SF
sterile_fileTL3Regular23 Dec 2024 · edited#101

I would keep building a sensible monitoring schedule and the decision it usually gets used for separate in this thread. They are related and they are not the same question, and merging them is why the last one went badly.

3 likes 19mo
LC
l.cabreraTL223 Dec 2024#102

Post #100 describes the usual case. This is about the unusual one.

Repeat before acting is standard practice for an isolated abnormal result on most analytes, and it is standard for a reason.

I have written this out at length because the short version keeps being misread.

10 likes 19mo
F
FairweatherTL2Member23 Dec 2024#103

On building a sensible monitoring schedule the community has more anecdote than the confidence in this thread implies, and I include my own contribution in that.

30 likes 19mo
KB
ka.batistaTL223 Dec 2024#104
h.amankwah, post #100: A trend needs at least three points to be a trend. Two points are a line and a line through noise is still a line. Worth saying I have only my own numbers here, and n is small. Go to post

The practical version of building a sensible monitoring schedule is three sentences long. The rigorous version is three pages and reaches the same conclusion with the conditions attached.

0 likes in reply to #100 19mo
VT
vial_tableTL2Member23 Dec 2024#105
cannula_trace, post #20: Genuine question rather than a rhetorical one: has anyone here actually observed building a sensible monitoring schedule, as opposed to read about it? The thread is long and I cannot tell. Go to post

A trend needs at least three points to be a trend. Two points are a line and a line through noise is still a line.

I would treat that as a working assumption and revisit it.

6 likes in reply to #20 19mo
DV
d.vestergaardTL223 Dec 2024#106

Grateful for the specificity. Vague answers to this question are what sent me looking.

15 likes 19mo
IL
integrator_logTL3Regular23 Dec 2024#107

Post #105 is the version of this I will quote in future. One addition.

Careful with the language on building a sensible monitoring schedule. "Not detected" and "not present" are different findings and the first is a statement about the method.

0 likes 19mo
SS
s.salgadoTL223 Dec 2024#108
a.reyes, post #92: Post #91 put the caveat in the right place and I want to underline it. Building a sensible monitoring schedule sits at the boundary between what this community can usefully discuss and what it cannot, and I think it falls on the discussable side, narrowly. Go to post

Building a sensible monitoring schedule looks different depending on whether you are reading the primary literature or the summaries of it, and the difference is not in our favour.

1 like in reply to #92 19mo
VK
v.klausenTL3Regular23 Dec 2024#109
j.sandvik, post #55: Adding what did not work for me on building a sensible monitoring schedule, since the failures never get written up and they are half the useful information. Go to post

Glycaemic markers integrate over different periods. A point glucose and a longer-term marker disagreeing is not a contradiction; it is two different questions.

0 likes in reply to #55 19mo

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