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Sourcing · Independent verification

Choosing which test to pay for, given a fixed budget — does this still hold?

AK
ak.kravchenkoTL215 Oct 2024#1

Choosing which test to pay for, given a fixed budget — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below.

A question about how a record should be read rather than about a supplier.

We have results from Janoshik and from PeptideMeter on the same product line, months apart, agreeing closely. My question is what that agreement actually establishes, given that neither saw the other's sample.

I suspect the honest answer is narrower than it feels, and I would like it stated precisely.

12 likes 21mo
MS
m.strand_rphTL3Pharmacist17 Oct 2024#2

Narrowing the opening post, because the general version has more than one answer.

Repeat determination on the same product line months apart is the measurement that speaks to consistency, and consistency is what most buyers actually want.

Posted with less confidence than the sentence structure implies.

1 like 21mo
AP
a.pereiraTL218 Oct 2024#3

A record with four results over sixteen months is a thin record rather than a bad one, and the honest description says which.

I have said this before in a thread nobody could find, so it is worth repeating.

32 likes 21mo
PE
ppm_errorTL3Analytical chemist20 Oct 2024#4

It does not extend to lots nobody has seen, it is not a recommendation, and it says nothing about anything other than what was measured.

17 likes 21mo
NC
n.cardosoTL221 Oct 2024#5
a.pereira, post #3: A record with four results over sixteen months is a thin record rather than a bad one, and the honest description says which. I have said this before in a thread nobody could find, so it is worth repeating. Go to post

Repeat testing: if you want to verify the same lot a second time, testing with a different service strengthens the conclusion. Testing with the same service verifies reproducibility but uses the same method.

3 likes in reply to #3 21mo
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preregisteredTL3Research methods22 Oct 2024#6

The record shows what was measured. Everything beyond that is inference and this site tries to keep the line visible.

0 likes 21mo
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n.vukovicTL223 Oct 2024#7

Worth separating two things that post #5 runs together.

Repeat determination on the same product line months apart is the measurement that speaks to consistency, and consistency is what most buyers actually want.

A partial answer, offered because a partial answer beats none.

24 likes 21mo
OL
o.lindgrenTL2Regular24 Oct 2024#8

A record with four results over sixteen months is a thin record rather than a bad one, and the honest description says which.

I would want to see it done twice before believing it once.

11 likes 21mo
YI
y.ibarraTL225 Oct 2024#9

It does not extend to lots nobody has seen, it is not a recommendation, and it says nothing about anything other than what was measured.

I have deliberately not rounded that, because the rounding is where the argument starts.

16 likes 21mo
PN
plateau_notesTL2Regular26 Oct 2024#10
preregistered, post #6: The record shows what was measured. Everything beyond that is inference and this site tries to keep the line visible. Go to post

A record with four results over sixteen months is a thin record rather than a bad one, and the honest description says which.

6 likes in reply to #6 21mo
SD
s.demirTL227 Oct 2024#11

Taking post #10 at face value and following it one step further.

Repeat determination on the same product line months apart is the measurement that speaks to consistency, and consistency is what most buyers actually want.

That much is documented. The rest is how I have interpreted it.

0 likes 21mo
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RidgewayTL3Regular28 Oct 2024#12

Post #8 and I disagree about the size of the effect, not about the direction.

The record shows what was measured. Everything beyond that is inference and this site tries to keep the line visible.

The step people skip is the one I have spelled out.

0 likes 21mo
ID
i.dumitruTL229 Oct 2024#13

Repeat testing: if you want to verify the same lot a second time, testing with a different service strengthens the conclusion. Testing with the same service verifies reproducibility but uses the same method.

8 likes 21mo
EL
endpoint_lineTL3Regular30 Oct 2024 · edited#14
n.cardoso, post #5: Repeat testing: if you want to verify the same lot a second time, testing with a different service strengthens the conclusion. Testing with the same service verifies reproducibility but uses the same method. Go to post

It does not extend to lots nobody has seen, it is not a recommendation, and it says nothing about anything other than what was measured.

20 likes in reply to #5 21mo
IG
in.guerreroTL231 Oct 2024#15
Ridgeway, post #12: Post #8 and I disagree about the size of the effect, not about the direction. The record shows what was measured. Everything beyond that is inference and this site tries to keep the line visible. The step people skip is the one I have spelled out. Go to post

Building on post #14 rather than restating it.

Repeat determination on the same product line months apart is the measurement that speaks to consistency, and consistency is what most buyers actually want.

I checked the source rather than the summary, and they differ.

28 likes in reply to #12 21mo
HN
h.nicolaidesTL3Regular1 Nov 2024#16

The record shows what was measured. Everything beyond that is inference and this site tries to keep the line visible.

0 likes 21mo
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p.onwukaTL22 Nov 2024#17

A record with four results over sixteen months is a thin record rather than a bad one, and the honest description says which.

The reasoning is more useful than the number, which is why I have shown it.

5 likes 21mo
LA
l.aaltonenTL3Regular3 Nov 2024#18

Everything in post #16 holds. The case it does not cover is the one I have.

It does not extend to lots nobody has seen, it is not a recommendation, and it says nothing about anything other than what was measured.

That is the honest state of it as of this week.

14 likes 21mo
DN
d.ndiayeTL24 Nov 2024 · edited#19

Repeat testing: if you want to verify the same lot a second time, testing with a different service strengthens the conclusion. Testing with the same service verifies reproducibility but uses the same method.

0 likes 21mo
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WickramasingheTL2Member5 Nov 2024#20

Repeat determination on the same product line months apart is the measurement that speaks to consistency, and consistency is what most buyers actually want.

4 likes 21mo
AV
a.villalobosTL26 Nov 2024#21
p.onwuka, post #17: A record with four results over sixteen months is a thin record rather than a bad one, and the honest description says which. The reasoning is more useful than the number, which is why I have shown it. Go to post

Post #17 and I disagree about the size of the effect, not about the direction.

The record shows what was measured. Everything beyond that is inference and this site tries to keep the line visible.

20 likes in reply to #17 21mo
SS
s.stavrianosTL2Member6 Nov 2024#22

Taking post #21 at face value and following it one step further.

Repeat testing: if you want to verify the same lot a second time, testing with a different service strengthens the conclusion. Testing with the same service verifies reproducibility but uses the same method.

Noting that the question and the thing people usually mean by it are different.

8 likes 21mo
EK
ew.kuuselaTL27 Nov 2024#23

Repeat determination on the same product line months apart is the measurement that speaks to consistency, and consistency is what most buyers actually want.

Two people can read the same figure differently here and both be reasonable.

2 likes 21mo
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DSakamotoTL3Regular8 Nov 2024#24

Bookmarking this. I will come back when I have something worth adding.

0 likes 21mo
TB
t.brandtTL29 Nov 2024 · edited#25
l.aaltonen, post #18: Everything in post #16 holds. The case it does not cover is the one I have. It does not extend to lots nobody has seen, it is not a recommendation, and it says nothing about anything other than what was measured. That is the honest state of it as of this week. Go to post

It does not extend to lots nobody has seen, it is not a recommendation, and it says nothing about anything other than what was measured.

14 likes in reply to #18 21mo
BT
baseline_tableTL2Member10 Nov 2024#26

This follows post #25 rather than contradicting it.

A record with four results over sixteen months is a thin record rather than a bad one, and the honest description says which.

5 likes 21mo
AC
a.coelhoTL211 Nov 2024#27
KB
k.bettencourtTL2Member11 Nov 2024#28
baseline_table, post #26: This follows post #25 rather than contradicting it. A record with four results over sixteen months is a thin record rather than a bad one, and the honest description says which. Go to post

It does not extend to lots nobody has seen, it is not a recommendation, and it says nothing about anything other than what was measured.

Filing this under things that are true until someone shows me otherwise.

0 likes in reply to #26 21mo
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v.stanescuTL212 Nov 2024#29

The record shows what was measured. Everything beyond that is inference and this site tries to keep the line visible.

If anyone can point at the primary source I would be grateful.

9 likes 20mo
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aliquot_lineTL3Regular13 Nov 2024#30

Repeat testing: if you want to verify the same lot a second time, testing with a different service strengthens the conclusion. Testing with the same service verifies reproducibility but uses the same method.

I would rather post the uncertainty than round it away.

2 likes 20mo