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Coming back to: Official shortage notices and what they authorise

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s.poulsenTL3Regular2 May 2025#1

Official shortage notices and what they authorise Writing it up because I had to work it out twice and would rather nobody else did.

Official shortage notices — I have the observation and I do not trust my interpretation of it, so I am posting the observation and holding the interpretation back.

Numbers, method and the conditions under which they were collected are below. Interpret them however they warrant.

3 likes 15mo
VB
v.bhattacharyaTL25 May 2025#2

Supply interruptions: official shortage notices are published by regulatory agencies. That is the correct primary source rather than pharmacy rumors or forum discussion.

0 likes 15mo
AK
a.kowalskiTL28 May 2025#3

Compounding during shortages: some jurisdictions allow pharmacy compounding when a marketed product is in shortage. That permission is jurisdiction-specific and time-limited (usually for the duration of the shortage).

Genuinely open to being wrong about this one.

17 likes 15mo
TW
t.wojcikTL210 May 2025#4

The opening post is right about the mechanism and I think understates the practical bit.

Managing an unplanned gap: if a shortage causes a gap in treatment, the questions are how long the gap will be and how that affects your condition. Discussing with your clinician is prudent if the gap is weeks or longer.

Flagging that the sources on this are thinner than the confidence in the thread suggests.

6 likes 15mo
FA
f.amankwahTL212 May 2025#5
v.bhattacharya, post #2: Supply interruptions: official shortage notices are published by regulatory agencies. That is the correct primary source rather than pharmacy rumors or forum discussion. Go to post

On the opening post — agreed on the reasoning, with one qualification.

An update on my earlier Official shortage notices post: the pattern held for another six weeks and then stopped, which I did not predict and cannot explain.

0 likes in reply to #2 15mo
EP
e.piresTL213 May 2025#6

Picking up post #5: that is the part I would want checked first.

Official shortage notices sits at the boundary between what this community can usefully discuss and what it cannot, and I think it falls on the discussable side, narrowly.

32 likes 15mo
CO
c.ostergaardTL215 May 2025#7

Anyone reporting availability should say the region and the date, because both determine whether the report is usable.

If that is already documented somewhere, ignore me and link it.

11 likes 14mo
HS
hana.satoTL4 Moderator17 May 2025#8
f.amankwah, post #5: On the opening post — agreed on the reasoning, with one qualification. An update on my earlier Official shortage notices post: the pattern held for another six weeks and then stopped, which I did not predict and cannot explain. Go to post

I came in to disagree and I am leaving without a disagreement.

3 likes in reply to #5 14mo
HB
h.bakkerTL218 May 2025#9

Shortage status determines what compounding is permitted in some jurisdictions, which links two questions that otherwise seem unrelated.

It took me longer than it should have to see that.

6 likes 14mo
MS
m.strand_rphTL3Pharmacist20 May 2025#10
v.bhattacharya, post #2: Supply interruptions: official shortage notices are published by regulatory agencies. That is the correct primary source rather than pharmacy rumors or forum discussion. Go to post

Building on post #9 rather than restating it.

Stockpiling in response to a shortage worsens it, which is true and is a poor argument to make to somebody who has run out.

Filing this under things that are true until someone shows me otherwise.

1 like in reply to #2 14mo
SB
s.bruunTL221 May 2025#11

Summarising the Official shortage notices thread so far, since it is long and the answer is buried: the first reply has the method, the fourth has the correction to it, and the rest is people agreeing at length.

6 likes 14mo
GR
g.rasmussenTL223 May 2025#12
v.bhattacharya, post #2: Supply interruptions: official shortage notices are published by regulatory agencies. That is the correct primary source rather than pharmacy rumors or forum discussion. Go to post

Dose hold versus tapering: if a temporary shortage forces a gap, holding your dose and resuming when supply returns is different from gradually tapering. The two are different decisions.

That is all I can say without guessing.

16 likes in reply to #2 14mo
MP
mira.patelTL424 May 2025#13
MO
m.onwukaTL225 May 2025#14

International supply chains: a shortage in one country does not mean shortage in another. That is why ordering from multiple suppliers before a shortage gets bad is prudent if you can.

The conclusion is tentative; the arithmetic underneath it is not.

1 like 14mo
OB
owen.bradyTL4 Moderator27 May 2025#15

Pharmacy-level availability varies enormously during a shortage, so two honest accounts from the same city can be opposite.

3 likes 14mo
RS
r.serranoTL228 May 2025#16

Post #12 put the caveat in the right place and I want to underline it.

A shortage of one presentation is not a shortage of all of them, and the published notices are specific about which.

11 likes 14mo
PP
peak_purityTL3Analytical chemist30 May 2025#17
hana.sato, post #8: I came in to disagree and I am leaving without a disagreement. Go to post

Switching presentation or strength during a shortage is a prescribing decision rather than a substitution anybody should improvise.

I would put a moderate confidence on that and no more.

32 likes in reply to #8 14mo
JE
j.erdoganTL231 May 2025#18

No notes. Posting so the count is not one.

0 likes 14mo
NG
np_gilmoreTL3Nurse practitioner1 Jun 2025#19
a.kowalski, post #3: Compounding during shortages: some jurisdictions allow pharmacy compounding when a marketed product is in shortage. That permission is jurisdiction-specific and time-limited (usually for the duration of the shortage). Genuinely open to being wrong about this one. Go to post

Post #17 is the version of this I will quote in future. One addition.

Where a shortage forces a gap, the pharmacokinetics mean a missed week is a perturbation rather than a reset, which is worth knowing.

16 likes in reply to #3 14mo
MV
m.vukovicTL23 Jun 2025#20
c.ostergaard, post #7: Anyone reporting availability should say the region and the date, because both determine whether the report is usable. If that is already documented somewhere, ignore me and link it. Go to post

I read the earlier replies on Official shortage notices twice before writing this, because I had assumed the opposite and wanted to be sure I was disagreeing with what was said rather than what I expected.

31 likes in reply to #7 14mo
MA
m.agyemanTL24 Jun 2025#21
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taper_tableTL3Regular5 Jun 2025#22

Appreciated. The plain phrasing does more work here than a longer post would.

0 likes 14mo
AH
a.hartmannTL26 Jun 2025#23
g.rasmussen, post #12: Dose hold versus tapering: if a temporary shortage forces a gap, holding your dose and resuming when supply returns is different from gradually tapering. The two are different decisions. That is all I can say without guessing. Go to post

Reports that a pharmacy has stock are the least durable information on the site and are still worth posting with a date.

I have written this out at length because the short version keeps being misread.

23 likes in reply to #12 14mo
EC
excursion_checkTL3Regular8 Jun 2025 · edited#24

Official shortage notices has a well-known answer and a correct answer, and the interesting work is establishing that they are the same. Nobody has done that here yet.

10 likes 14mo
KH
k.haddadTL29 Jun 2025#25

Worth separating two things that post #23 runs together.

Shortages end and the notices are updated. Checking the current notice takes a minute and is more reliable than a thread from March.

Noting that the question and the thing people usually mean by it are different.

0 likes 14mo
BM
buffer_marginTL3Regular10 Jun 2025#26
np_gilmore, post #19: Post #17 is the version of this I will quote in future. One addition. Where a shortage forces a gap, the pharmacokinetics mean a missed week is a perturbation rather than a reset, which is worth knowing. Go to post

This follows post #25 rather than contradicting it.

Manufacturer allocation decisions during a shortage are commercial and are rarely explained, which is frustrating and is not evidence of anything.

32 likes in reply to #19 14mo
TA
t.abubakarTL211 Jun 2025#27

Official shortage notices: I would want to see the raw numbers rather than the summary before agreeing. Summaries lose exactly the information that would settle this.

16 likes 14mo
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PSkarbekTL3Regular12 Jun 2025#28

The most useful contribution is a link to the current official notice rather than an account of one pharmacy.

I would treat that as a working assumption and revisit it.

6 likes 14mo
CS
c.serranoTL214 Jun 2025#29

Agreed, and I will stop repeating the version of this I had been repeating.

0 likes 13mo
TN
t.nardoneTL3Regular15 Jun 2025#30
v.bhattacharya, post #2: Supply interruptions: official shortage notices are published by regulatory agencies. That is the correct primary source rather than pharmacy rumors or forum discussion. Go to post

Picking up post #28: that is the part I would want checked first.

The arithmetic on Official shortage notices is the easy part and it is where the errors are, which is an uncomfortable combination. Show your working and someone will catch it.

24 likes in reply to #2 13mo