np_gilmore
TL3 Nurse practitioner · Perth, AU
Nurse practitioner in a metabolic clinic. Injection technique, site rotation, and the practical side of adherence.
Joined 22 January 2025 · last posted 6h · groups: clinicians, wiki-editors
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Revisiting: Drawing from a pen cartridge with a syringe: how the risk profile changes Replied, post #3 · Devices › Pens & autoinjectors · 28 Jul 2026 · 3 likes The opening post and I disagree about the size of the effect, not about the direction. Air in a cartridge behaves differently from air in a syringe because the…
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Follow-up: Reading an interaction checker output critically Replied, post #52 · Practice › Interactions · 18 Jul 2026 · 0 likes On post #51 — agreed on the reasoning, with one qualification. Where a published interaction study exists it usually reports an area-under-curve ratio, and that number…
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Coming back to: Preparing for an appointment: one page, three questions Replied, post #8 · Clinical › Prescriber conversations · 17 Jul 2026 · 12 likes Picking up post #7: that is the part I would want checked first. Bringing a record of symptoms with dates and severities makes an assessment materially easier and is…
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What is genuinely unknown about long-term amylin agonism Replied, post #46 · Compounds › Cagrilintide & amylin analogues · 17 Jul 2026 · 17 likes The monoisotopic mass sits near 3749.9 Da, and the same caveat applies as everywhere else: a mass consistent with the proposed structure is a necessary condition and…
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eGFR fluctuation and the creatinine denominator problem — the long version Replied, post #5 · Clinical › Bloodwork · 15 Jul 2026 · 2 likes I had written a reply contradicting post #3 and deleted it. Here is what survived. TSH and free hormones: TSH is a reasonable screening test but does not tell you about…
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Reflectance and photometric devices: precision in practice — a second dataset Replied, post #71 · Analytics › Home & field testing · 12 Jul 2026 · 5 likes A home refractometer is not measuring what people hope it is measuring in these preparations, and the readings are dominated by everything other than the peptide.
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Osteoarthritis and mechanical versus metabolic improvement — one year on Replied, post #44 · Clinical › Comorbidities · 12 Jul 2026 · 12 likes Worth separating two things that post #40 runs together. PCOS and metabolic overlap: polycystic ovary syndrome has metabolic overlap with obesity and insulin…
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Reading a home test result without over-claiming Replied, post #109 · Analytics › Home & field testing · 7 Jul 2026 · 4 likes The most useful home practice is not a test at all: photograph the vial, the cake, the label and the document on arrival. It costs nothing and it is the evidence you…
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Muscle cramps: the ordinary causes before the exotic ones — a second dataset Replied, post #28 · Practice › Side effects · 3 Jul 2026 · 7 likes Severe, persistent abdominal pain, especially radiating to the back, is in a different category from ordinary gastrointestinal upset and is a reason to seek medical…
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Journal club: orforglipron phase 2 and the non-peptide question Replied, post #109 · Evidence › Journal club · 3 Jul 2026 · 0 likes Recording who prepared each section makes the summary attributable, which matters when somebody reads it eighteen months later and wants to ask a question.
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Endotoxin and why it is a separate question from purity — what changed since Replied, post #63 · Analytics › Impurities & related substances · 1 Jul 2026 · 3 likes Picking up post #60: that is the part I would want checked first. Truncation products are substantially lower in mass and usually well separated chromatographically,…
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Sulfonylureas: the interaction most worth taking seriously — what changed since Replied, post #4 · Practice › Interactions · 1 Jul 2026 · 0 likes Research-use-only compounds have no interaction data of any kind, because interaction studies are done on medicines being developed for use in people.
Maintains 4 documents
- Survodutide — referenceReview due 20 Jan 2027
- Growth-hormone-releasing peptides (GHRP class) — referenceReview due 14 Mar 2027
- Ipamorelin — referenceReview due 13 Mar 2027
- STEP 3 — trial digestReview due 27 Jan 2027