Post #3 put the caveat in the right place and I want to underline it.
A symptom that starts weeks after a dose has been stable is a different observation from one that starts after an escalation, and it deserves a different explanation.
Post #3 put the caveat in the right place and I want to underline it.
A symptom that starts weeks after a dose has been stable is a different observation from one that starts after an escalation, and it deserves a different explanation.
The published rates come from populations that were titrated on a defined schedule with clinical supervision. Rates from a forum are not comparable and are biased by who chooses to post.
Adding what did not work for me on Dizziness on standing, since the failures never get written up and they are half the useful information.
Post #37 and I disagree about the size of the effect, not about the direction.
The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of an inactive preparation.
If anyone can point at the primary source I would be grateful.
Post #56 is right about the mechanism and I think understates the practical bit.
My position on Dizziness on standing is current rather than settled. I have revised it once already and I expect to again, so treat it accordingly.
Where the Dizziness on standing reasoning breaks down for me is the step from the group result to the individual case. That step is almost never argued for.
Reading back through the Dizziness on standing threads from last year, the same three questions come up every time and only one of them has ever been answered properly. That seems like a documentation gap rather than a knowledge gap.
The published rates come from populations that were titrated on a defined schedule with clinical supervision. Rates from a forum are not comparable and are biased by who chooses to post.
I would put this at better than even and not much better.
Read the full topic (95 posts)
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Why side effects reset at each escalation and that is not a failure
Why side effects reset at each escalation and that is not a failure — that is the question, and I have not found it answered plainly anywhere I have looked. The question about side effects that I actually…
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+3 | 7 | 11k | 14h |
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Dizziness on standing and the electrolyte explanation
On the subject in the title: Dizziness on standing and the electrolyte explanation Working notes rather than a conclusion. Trying to work out what would count as evidence on dizziness on standing, before…
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+3 | 7 | 147 | 4mo |
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A side-effect grading scheme this community uses, and its limits — the long version
A side-effect grading scheme this community uses, and its limits — the long version — setting out what I have, and where I think it stops being reliable. A narrow question about side-effect grading scheme,…
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+19 | 23 | 29k | 20mo |
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Taste changes and food aversion, reported and discussed
Posting this under the heading it deserves: Taste changes and food aversion, reported and discussed Everything below is what sits behind that. The question about taste changes and food aversion that I…
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+40 | 47 | 28k | 20mo |
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[2026 update] Reflux appearing for the first time at a dose step
Posting this under the heading it deserves: Reflux appearing for the first time at a dose step Everything below is what sits behind that. Reporting something rather than asking about it, in case the pattern…
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2 | 980 | 7mo |
| Topic | Participants | Replies | Views | Activity |
|---|---|---|---|---|
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The headache that turns out to be dehydration — the long version
On the subject in the title: The headache that turns out to be dehydration — the long version Working notes rather than a conclusion. A narrow question about headache, deliberately narrow, because the broad…
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+68 | 73 | 1.3k | 12h |
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Follow-up: Oral contraceptives and delayed emptying: what the data shows
Oral contraceptives and delayed emptying: what the data shows — setting out what I have, and where I think it stops being reliable. A follow-up question about Oral contraceptives and delayed emptying that I…
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+31 | 35 | 13k | 18mo |
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Whether protein timing matters at a large deficit
Posting this under the heading it deserves: Whether protein timing matters at a large deficit Everything below is what sits behind that. A follow-up question about whether protein timing that I did not know…
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+29 | 33 | 7.7k | 4mo |
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About the Adverse events category
Serious and unexpected events, how to document them, and where to report them officially. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its…
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+2 | 6 | 8.7k | 2d |
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Revisiting: Taste changes and food aversion, reported and discussed
Revisiting: Taste changes and food aversion, reported and discussed Writing it up because I had to work it out twice and would rather nobody else did. Two things I would like separated before anyone answers…
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+20 | 25 | 4.3k | 1d |