A symptom that starts weeks after a dose has been stable is a different observation from one that starts after an escalation, and it deserves a different explanation.
6 likes 8mo
A symptom that starts weeks after a dose has been stable is a different observation from one that starts after an escalation, and it deserves a different explanation.
Post #2 is right about the mechanism and I think understates the practical bit.
I would be cautious about generalising from the dizziness on standing example above. It is a good example. It is one example.
Coming back to the opening post, because the follow-up matters more than the original answer.
A definition problem is doing most of the work in this dizziness on standing discussion. Once the term is pinned down I suspect the disagreement mostly goes away and what is left is small.
The number people quote for dizziness on standing is a central estimate presented without its interval, and the interval is wide enough that the estimate is nearly uninformative on its own.
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