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Topic summary

Pancreatitis history and the risk calculus

This is a generated summary. It shows the 5 most-liked posts from a topic of 33, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.
LD
l.dziedzicTL2 Solution14 Apr 2026#3

Picking up the opening post: that is the part I would want checked first.

I keep a log for pancreatitis history specifically because my memory of it turned out to be systematically wrong in one direction. Six weeks of notes cost nothing and settled it.

7 likes 3mo
AI
a.ibarraTL224 Apr 2026#5
k.roos, post #2: Right — I had this wrong and I am glad to have read it before it mattered. Go to post

Medullary thyroid carcinoma (personal or family history) or multiple endocrine neoplasia type 2: absolute contraindication. The rodent preclinical signal is real enough to exclude this population.

I would be glad to be shown a cleaner way of putting this.

25 likes in reply to #2 3mo
JI
j.ivaturiTL28 Jun 2026#17
KLindqvist, post #6: A history of pancreatitis appears in the cautions and the decision around it needs somebody who knows the history rather than a general rule. A single observation, in a thread that deserves better than single observations. Go to post

Answering the question post #13 raises rather than the one it answers.

History of pancreatitis: these compounds can rarely trigger pancreatitis. History of pancreatitis increases relative risk. That is a relative contraindication, not absolute, but requires monitoring.

That is what I would do. It may not be what is correct.

32 likes in reply to #6 2mo
NH
new_here_2026TL1Member27 Jun 2026#23

Sensible. I would want the same detail before I acted on it either.

32 likes 1mo
SC
s.chowdhuryTL3Regular10 Jul 2026#27

The failure mode on pancreatitis history is boring rather than dramatic. It is almost always the step everyone assumes was done correctly because it is too simple to get wrong.

24 likes 18d

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