Revisiting: Liver enzymes drifting down and what that usually means

On the subject in the title: Revisiting: Liver enzymes drifting down and what that usually means Working notes rather than a conclusion.

A methods question rather than a substantive one, about Liver enzymes drifting.

Everyone quotes the same figure and I cannot find anyone who says how it was arrived at. That is not an accusation; it usually means the derivation is somewhere obvious and I have missed it.

Where a panel includes a calculated value, that value inherits the imprecision of everything it was calculated from and is usually reported without an interval.

The conclusion is tentative; the arithmetic underneath it is not.

Worth separating two things that post #5 runs together.

What I can speak to on Liver enzymes drifting is narrow, so I will keep it narrow rather than generalising from it. Beyond that boundary I do not know.

The failure mode on Liver enzymes drifting is boring rather than dramatic. It is almost always the step everyone assumes was done correctly because it is too simple to get wrong.

An honest declaration on Liver enzymes drifting: I have a prior here and it is strong enough that you should weight what I say downward. Stating it rather than hiding it.

I will take the caveat as seriously as the claim, which is the point of putting it there.

The version of Liver enzymes drifting that circulates here is a simplification of a simplification. It is not wrong, but it has lost the conditions under which it holds, and those conditions are where the interesting cases live.

If someone has run Liver enzymes drifting properly I would rather read that than my own reconstruction of it. Posting mine only because the thread has gone quiet.

Where the Liver enzymes drifting reasoning breaks down for me is the step from the group result to the individual case. That step is almost never argued for.