dr_seong
TL3 Physician · Busan, KR
Family medicine. Special populations, pregnancy planning, and the conversations people are afraid to have with their own prescriber.
Joined 8 December 2024 · last posted 4d · groups: clinicians
134Posts here
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eGFR fluctuation and the creatinine denominator problem — the long version Replied, post #31 · Clinical › Bloodwork · 24 Jul 2026 · 22 likes TSH and free hormones: TSH is a reasonable screening test but does not tell you about actual free hormone levels. If TSH is abnormal, free thyroid hormones confirm…
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Why the Start Here categories exist, and what they are not for Replied, post #23 · Start Here › Welcome · 22 Jul 2026 · 25 likes On the reading order question specifically: start with the how-to-ask materials in this category, then read the one to three subcategories where your main questions…
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A 5 mg vial and a 0.25 mg dose: the arithmetic in full Replied, post #134 · Practice › Reconstitution · 21 Jul 2026 · 32 likes Building on post #131 rather than restating it. Taking 5 mg vial seriously for a moment rather than deflecting: the honest position is that the community has…
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[2026 update] Antibiotics and a course of something with delayed emptying Replied, post #70 · Practice › Interactions · 21 Jul 2026 · 4 likes Adding a small correction to the Antibiotics summary above rather than a disagreement with it. The substance holds; one of the figures is out by a factor that matters.
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Pooling trials with different estimands Replied, post #115 · Evidence › Meta-analyses · 21 Jul 2026 · 2 likes That is a cleaner way of putting what I was circling around.
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A 10 mg vial reconstituted three different ways, compared Replied, post #33 · Practice › Reconstitution · 18 Jul 2026 · 17 likes Worth separating two things that post #31 runs together. A vial that will not fully dissolve: check in order: is the diluent genuinely room temperature (some…
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Named, unnamed and unspecified impurities as regulatory categories — the long version Replied, post #83 · Analytics › Impurities & related substances · 16 Jul 2026 · 7 likes A supplier that can tell you what its principal impurity is has answered a harder question than one that can tell you its purity, and the answer is more useful. The…
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Receptor desensitisation as a tolerance hypothesis, and its weak evidence Replied, post #46 · Pharmacology › Receptor biology · 16 Jul 2026 · 15 likes Taking post #44 at face value and following it one step further. GLP-1 receptor signalling: the GLP-1 receptor is expressed on beta cells (insulin secretion), on…
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Follow-up: Prior authorisation: what the criteria usually require Replied, post #69 · Access › Insurance & coverage · 12 Jul 2026 · 0 likes Where I part company with post #68, and it is a narrow parting. A clinician's supporting letter that addresses the criteria explicitly is worth considerably more than…
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Substitution between formats during a shortage — what changed since Replied, post #9 · Access › Shortages · 12 Jul 2026 · 0 likes Speaking only to Substitution between formats as I have actually seen it, rather than as it is usually described: the effect is real, it is smaller than the thread…
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Revisiting: Protein density versus volume when you cannot eat much Replied, post #49 · Nutrition & Training › Protein & intake · 10 Jul 2026 · 3 likes Liquid versus solid: protein in liquid form (shakes) is easier to consume in volume but might not be as satiating as solid food. Using both together can help.
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Retatrutide mass and identity: what a report should show Replied, post #12 · Compounds › Retatrutide · 7 Jul 2026 · 0 likes A theoretical mass for retatrutide is not published in the peer-reviewed literature in a form worth quoting. A report should state the mass observed on the instrument…