The Peptide CommonsEst. May 2024
Independent. We sell nothing and are affiliated with no manufacturer or pharmacy. Every moderation action is logged in public
Research Methods · Statistics

Second pass at: Multiplicity when you track fifteen variables

KF
k.fonsecaTL220 Oct 2024#1

Posting this under the heading it deserves: Second pass at: Multiplicity when you track fifteen variables Everything below is what sits behind that.

Two things I would like separated before anyone answers on Multiplicity, because they get bundled and then argued about as one thing.

The first is descriptive: what has actually been observed, by whom, and how. The second is causal: why. I am asking about the first only.

60 likes 21mo
FF
f.fontaineTL220 Dec 2024#2

I have three months of notes on Multiplicity and the honest summary is that the trend is real and the week-to-week numbers are noise. I nearly drew the opposite conclusion from the first fortnight.

0 likes 19mo
RM
r.marsdenTL3Regular2 Feb 2025#3
f.fontaine, post #2: I have three months of notes on Multiplicity and the honest summary is that the trend is real and the week-to-week numbers are noise. I nearly drew the opposite conclusion from the first fortnight. Go to post

Taking the opening post at face value and following it one step further.

Multiplicity and multiple comparisons: if you test many hypotheses, the chance of finding a false positive by random chance increases. That is why pre-specifying the primary hypothesis matters.

Noting that the question and the thing people usually mean by it are different.

6 likes in reply to #2 18mo

Suggested topics

TopicParticipantsRepliesViewsActivity
Regression to the mean in progress reports
On the subject in the title: Regression to the mean in progress reports Working notes rather than a conclusion. Something about regression does not reconcile and I would like a second pair of eyes before I…
HAAMTFAVDM+30 34 49k 12mo
[2026 update] Correlation in a self-tracked dataset: what it can support
Posting this under the heading it deserves: Correlation in a self-tracked dataset: what it can support Everything below is what sits behind that. Posting a small dataset on Correlation. It is mine, it is…
GTARLS 2 31k 6h
What a confidence interval means, from scratch
What a confidence interval means, from scratch — that is the question, and I have not found it answered plainly anywhere I have looked. Asking about confidence interval directly, because I have read four…
MHSNO 2 2.6k 2mo
Multiplicity when you track fifteen variables
Multiplicity when you track fifteen variables — setting out what I have, and where I think it stops being reliable. Asking about multiplicity directly, because I have read four threads on it and each answered…
JATNNA 2 60k 11mo
Measurement error in home scales, with a worked standard deviation — the long version
On the subject in the title: Measurement error in home scales, with a worked standard deviation — the long version Working notes rather than a conclusion. A narrow question about Measurement error in home…
SKRRAWDYJD+96 105 2k 2mo

Related topics — sharing the tags number needed to treat, confounding, effect size

TopicParticipantsRepliesViewsActivity
Fixed versus detachable needles: the trade-offs
Posting this under the heading it deserves: Fixed versus detachable needles: the trade-offs Everything below is what sits behind that. I was wrong about fixed versus detachable needles in a thread last spring…
HNAVPWSMRD+117 121 7.3k 18mo
Micro-titration: a disputed topic, argued properly
Micro-titration: a disputed topic, argued properly Writing it up because I had to work it out twice and would rather nobody else did. Two things I would like separated before anyone answers on…
ESKHVKASNP+99 110 61k 2d
Journal club: SUSTAIN 6 and its retinopathy signal — does this still hold?
The question in the title: Journal club: SUSTAIN 6 and its retinopathy signal — does this still hold? I will give what I have already checked below so nobody repeats it. Reading SUSTAIN 6 ( N Engl J Med ,…
RONSPPSDOB+60 66 12k 16mo
Titles that describe the question, not the situation — what changed since
Posting this under the heading it deserves: Titles that describe the question, not the situation — what changed since Everything below is what sits behind that. What changes if the standard account of Titles…
ACAWAPTDCR+29 33 29k 10mo
Revisiting: The arithmetic of an intermediate dose between two label steps
Revisiting: The arithmetic of an intermediate dose between two label steps Writing it up because I had to work it out twice and would rather nobody else did. I have read the maintained page on this and I…
CSRHGBWTMR+41 45 808 2mo