Vomiting: when it is expected and when it is a reason to stop posts 121–125

Coming back to post #119, because the follow-up matters more than the original answer.

Vomiting: when it is expected (first-dose reactions or early titration) and when it is a reason to stop and seek help are different. Occasional vomiting during titration is ordinary. Persistent vomiting or vomiting of a new character later in treatment warrants contact with your clinician.

This is where my knowledge stops and I would rather mark the edge than blur it.

Post #119 is right about the mechanism and I think understates the practical bit.

The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of an inactive preparation.

That is what the documentation says. What happens in practice is usually close.

The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of an inactive preparation.

I had written a reply contradicting post #124 and deleted it. Here is what survived.

The published rates come from populations that were titrated on a defined schedule with clinical supervision. Rates from a forum are not comparable and are biased by who chooses to post.

The right answer here may simply be that it has not been measured.