IMainwaring
TL3 Regular · Innsbruck, AT
Long-standing member. Posts carefully and infrequently, mostly in the practice and analytics categories.
Joined 2 October 2024 · last posted 10d
139Posts here
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Revisiting: Why the absence of controlled human data on BPC-157 matters more than people… Replied, post #39 · Compounds › Repair & healing peptides · 18 Jul 2026 · 2 likes Narrowing post #36, because the general version has more than one answer. The lyophilised cake is worth looking at before adding diluent. A collapsed or shrunken cake…
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Why pulsatile secretion matters for interpreting secretagogue claims Replied, post #7 · Compounds › Secretagogues & GH axis · 16 Jul 2026 · 3 likes Pulsatile secretion matters because growth hormone is secreted in pulses, not continuously. A single post-dose growth hormone level is nearly uninterpretable. Assessing…
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How shortages have affected compounding permissions Replied, post #39 · Access › Shortages · 14 Jul 2026 · 4 likes A note on scope: what I am saying about shortages applies to the case in the first post and I would not extend it further without checking.
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Revisiting: Journal club: SURMOUNT-OSA and a hard endpoint in a soft field Replied, post #103 · Evidence › Journal club · 13 Jul 2026 · 7 likes Post #102 answers the question as asked. The question underneath it is different. For anyone finding this later: the short answer on SURMOUNT-OSA is that it depends on…
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Private prescribing in the UK: what is actually involved Replied, post #63 · Regional › UK & Ireland · 12 Jul 2026 · 28 likes Private prescribing arrangements differ in what they include, and the differences are more consequential than the headline price.
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Seven-day rolling means and why weekly readings mislead Replied, post #10 · Outcomes › Progress reports · 10 Jul 2026 · 25 likes Weighing daily and reporting weekly is a better protocol than weighing weekly, because it separates the measurement frequency from the reporting frequency. That is what…
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Designing a personal experiment that could change your mind — one year on Replied, post #73 · Research Methods › N-of-1 designs · 10 Jul 2026 · 24 likes Write down what you would accept as evidence that it did not work, before starting. That one sentence turns an anecdote into an experiment. Anyone with a larger sample,…
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What is genuinely unknown about long-term amylin agonism Replied, post #20 · Compounds › Cagrilintide & amylin analogues · 10 Jul 2026 · 16 likes On storage: aggregation-prone peptides are the ones where repeated warming and cooling does the most damage, and where a solution that looks fine may already have…
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What published stability data actually covers, and what it does not Replied, post #10 · Practice › Storage & stability · 9 Jul 2026 · 0 likes On published stability data actually covers the community has more anecdote than the confidence in this thread implies, and I include my own contribution in that.
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Angle of injection and whether 90 degrees is always right — the long version Replied, post #41 · Practice › Administration · 8 Jul 2026 · 2 likes Quietly grateful for the plain phrasing. Not every thread gets that.
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Muscle cramps: the ordinary causes before the exotic ones — a second dataset Replied, post #34 · Practice › Side effects · 6 Jul 2026 · 33 likes Muscle cramps has a well-known answer and a correct answer, and the interesting work is establishing that they are the same. Nobody has done that here yet.
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How much context is too much context in a first post? Replied, post #18 · Start Here › How to Ask · 5 Jul 2026 · 0 likes On post #16 — agreed on the reasoning, with one qualification. A question about somebody else's post should be a reply to that post, not a new topic. A question the…