Ibrahimovi
TL2 Member · Dresden, DE
UK-based. Mostly the access and pricing categories.
Joined 11 June 2025 · last posted 8d · groups: regional-uk, regional-apac
78Posts here
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GIP receptor agonism and the argument about direction — does this still hold? Replied, post #12 · Pharmacology › Receptor biology · 20 Jul 2026 · 27 likes Building on post #9 rather than restating it. Biased agonism — where different ligands at the same receptor favour different downstream pathways — is a plausible…
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Reading order for a first week here, and what to skip until later — what changed since Replied, post #27 · Start Here › Welcome · 10 Jul 2026 · 0 likes Reading order: I would want to see the raw numbers rather than the summary before agreeing. Summaries lose exactly the information that would settle this.
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Request: a per-category review queue Replied, post #80 · Meta › Feature requests · 5 Jul 2026 · 3 likes Request that would help newcomers more than regulars: show the subcategory description on hover in the category list. The names are terse and the descriptions are good.
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Trust level 3 requirements: a clarification — does this still hold? Replied, post #71 · Meta › Announcements · 25 Jun 2026 · 7 likes Practical experience of Trust level 3 requirements, offered as one case with the conditions stated, not as a general finding. Conditions first, because they are what…
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[2026 update] Travelling with an injectable: documentation and practicalities Replied, post #4 · Access › International · 7 Jun 2026 · 8 likes Building on the opening post rather than restating it. Both are useful and they are different contributions. A first-hand account and a citation answer different halves…
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An appeal that succeeded, with the letter structure — the long version Replied, post #63 · Access › Insurance & coverage · 7 Jun 2026 · 0 likes Denial letters: the stated reason tells you exactly what to submit next. A denial is not final; it is a specification for an appeal. Reading the reason carefully and…
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Official shortage notices and what they authorise Replied, post #91 · Access › Shortages · 6 Jun 2026 · 15 likes This is the first time the answer has come with its own limits attached. Appreciated.
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A certificate whose chromatogram axes do not match its stated method — one year on Replied, post #97 · Sourcing › Red flags · 6 Jun 2026 · 16 likes Reporting rather than recommending, on certificate whose chromatogram axes. What happened is above. Whether it should have is a different question and not one I am…
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Endotoxin and why it is a separate question from purity — what changed since Replied, post #33 · Analytics › Impurities & related substances · 31 May 2026 · 6 likes Reframing Endotoxin slightly, because I think the disagreement is about the question rather than the answer. If the question is "does it happen", yes. If it is "how…
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Official shortage notices and what they authorise Replied, post #74 · Access › Shortages · 28 May 2026 · 27 likes Shortage predictions: regulators and suppliers issue shortage alerts before they become acute. Checking the regulatory website for shortages gives you advance notice.
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Micro-titration: a disputed topic, argued properly — one year on Replied, post #39 · Practice › Dosing & titration · 21 May 2026 · 3 likes Everything in post #35 holds. The case it does not cover is the one I have. Micro-titration sits at the boundary between what this community can usefully discuss and…
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What a certificate commits its issuer to — one year on Replied, post #71 · Analytics › COA interpretation · 19 May 2026 · 3 likes A chromatogram supplied as a small image is legible for peak shape and not for baseline detail. That is enough to sanity-check an integration and not enough to…