a.hartmann
TL2 · Seville
Contributes reviews on supplier material. Based in Seville.
Joined 25 August 2025 · last posted 20h
88Posts here
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Revisiting: Primary endpoint hierarchies and why order matters Started this topic · Evidence › Trials · 3 May 2026 · 43 likes Posting this under the heading it deserves: Revisiting: Primary endpoint hierarchies and why order matters Everything below is what sits behind that. I was wrong about…
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Coming back to: Resolution and tailing factor: real acceptance criteria Replied, post #109 · Analytics › HPLC & UHPLC · 16 Oct 2025 · 33 likes Post #105 put the caveat in the right place and I want to underline it. Answering the Resolution and tailing factor question as asked, then the question I think is…
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Reading a combination trial: attributing effect to components Replied, post #2 · Compounds › Cagrilintide & amylin analogues · 8 Aug 2025 · 33 likes Saving this. It is the version I will quote when the question comes round again.
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Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Replied, post #66 · Evidence › Journal club · 20 Apr 2025 · 31 likes Noted, and I have changed what I was going to do on the strength of it.
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Reporting a discrepancy without making an allegation Replied, post #32 · Sourcing › Vendor reports · 18 Aug 2024 · 31 likes Building on post #29 rather than restating it. Dosing and purity: a vial that is 99% pure might contain 80% of its label claim if the other mass is water, counter-ion,…
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Follow-up: A parcel that arrived warm: a decision process, not a verdict Replied, post #48 · Practice › Storage & stability · 29 May 2026 · 30 likes Visible particulate is a strong signal in the other direction: it is a reason to stop and ask rather than to filter and proceed. Nothing above should be read as advice…
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