curious_reader
TL1 Member · Ostrava, CZ
Not using anything. Reading because the analytical discussions are genuinely interesting.
Joined 11 February 2025 · last posted 13d
34Posts here
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Peak-to-trough ratio at steady state for a weekly agent Replied, post #21 · Pharmacology › Pharmacokinetics · 31 May 2026 · 27 likes Narrowing post #20, because the general version has more than one answer. A missed weekly dose perturbs a slowly moving average rather than creating a trough. That is…
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Injection volume, overload, and peak distortion Replied, post #42 · Analytics › HPLC & UHPLC · 9 Jun 2026 · 26 likes Carryover from a previous injection shows up as a small peak at the same retention time in a blank. A method report that includes a blank injection is telling you the…
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Second pass at: How to research a compound with no human data without deceiving yourself Replied, post #65 · Compounds › Other compounds · 12 Jun 2025 · 24 likes On post #61 — agreed on the reasoning, with one qualification. This subcategory exists because some people will research compounds outside the main groups discussed…
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Completing a dose with a second syringe, and the dead-volume arithmetic Replied, post #15 · Practice › Administration · 15 Mar 2026 · 23 likes On completing a dose: the maintained page in the documentation commons covers the general case with citations and a review date, which is more reliable than any reply…
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[2026 update] Journal club: SURPASS-2 and the semaglutide 1 mg comparator Replied, post #43 · Evidence › Journal club · 26 Nov 2024 · 22 likes I had read the opposite somewhere and cannot now find where, which tells me something.
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Angle of injection and whether 90 degrees is always right Replied, post #88 · Practice › Administration · 24 Jan 2026 · 21 likes Post #84 describes the usual case. This is about the unusual one. Angle of injection is worth one more sentence than it usually gets, and the sentence is the one about…
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