d.vukovic
TL2 · Bursa
Contributes reviews on supplier material. Based in Bursa.
Joined 11 December 2024 · last posted 1d
74Posts here
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Why the Start Here categories exist, and what they are not for Replied, post #45 · Start Here › Welcome · 27 Jul 2026 · 0 likes The Lounge is a real category rather than a dumping ground. The sourcing rule still applies there, which surprises people, but the register is looser and nobody minds a…
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[2026 update] Temperature indicator cards: worth asking for? Replied, post #25 · Sourcing › Logistics · 23 Jul 2026 · 4 likes I had written a reply contradicting post #23 and deleted it. Here is what survived. Peak periods and public holidays affect this more than any other factor and are…
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Endotoxin and why it is a separate question from purity — what changed since Replied, post #85 · Analytics › Impurities & related substances · 21 Jul 2026 · 24 likes Post #82 is right about the mechanism and I think understates the practical bit. Where the Endotoxin reasoning breaks down for me is the step from the group result to…
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Interim analyses and stopping rules Replied, post #30 · Evidence › Trials · 12 Jul 2026 · 19 likes Two questions I would want answered before drawing anything from the interim analyses and stopping rules data above: how were the cases selected, and what happened to…
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A 5 mg vial and a 0.25 mg dose: the arithmetic in full Replied, post #105 · Practice › Reconstitution · 30 Jun 2026 · 2 likes Preservative effectiveness is tested against a defined microbial challenge under defined conditions. It is not a licence to treat an entered vial as sterile…
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Injecting into an area that has become firm: why not to Replied, post #79 · Practice › Administration · 15 Jun 2026 · 26 likes Adding the measurement that post #76 says would settle it. Bleeding at the site is common and unremarkable at these needle gauges. Persistent bruising in the same area…
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Programming during a large energy deficit Replied, post #16 · Nutrition & Training › Resistance training · 13 Jun 2026 · 28 likes Maintaining load with reduced volume is a reasonable strategy during a deficit and appears in the published literature more than the reverse.
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Follow-up: Prior authorisation: what the criteria usually require Replied, post #10 · Access › Insurance & coverage · 7 Jun 2026 · 3 likes Reimbursement changes: a compound covered one year might not be the next. A formulary decision in January can change by April. Checking again before refilling saves…
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Comparing prices across jurisdictions without misleading yourself Replied, post #40 · Access › Pricing · 5 Jun 2026 · 10 likes Bookmarking this. I will come back when I have something worth adding.
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Fasting versus non-fasting and which tests care Replied, post #40 · Clinical › Bloodwork · 2 Jun 2026 · 0 likes Analytical imprecision: any measurement has an error margin. A small difference in consecutive tests is usually measurement noise, not a real change. Knowing the…
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Coming back to: Time to steady state after a dose increase Replied, post #66 · Pharmacology › Pharmacokinetics · 1 Jun 2026 · 0 likes Picking up post #64: that is the part I would want checked first. Loading doses are not used in this class and the pharmacokinetic reason is tolerability rather than…
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Second pass at: Programming during a large energy deficit Replied, post #3 · Nutrition & Training › Resistance training · 26 May 2026 · 1 like Machine-based work is often better tolerated when energy is low and is not inferior for this purpose.