g.radich

TL2 · Galway

Contributes reviews on supplier material. Based in Galway.

Joined 21 February 2025 · last posted 2d · groups: regional-apac

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Why chargeback is not the safety net people assume Replied, post #27 · Sourcing › Payments · 26 Jul 2026 · 0 likes An update on my earlier chargeback post: the pattern held for another six weeks and then stopped, which I did not predict and cannot explain.
Immortal time bias in a claims-database study — one year on Replied, post #28 · Evidence › Study critique · 17 Jul 2026 · 16 likes Helpful, and short, which on this subject is harder than long.
Journal club: what we got wrong in an earlier session Replied, post #84 · Evidence › Journal club · 14 Jul 2026 · 9 likes Nothing discussed in a session is advice to anybody, and clinician participants here say so themselves as a matter of course rather than because a rule requires it.
Why retatrutide discussion here is more cautious than elsewhere — one year on Replied, post #62 · Compounds › Retatrutide · 14 Jul 2026 · 17 likes Why this subcategory is more cautious than elsewhere: retatrutide is investigational, phase 3 is ongoing, and the heart-rate signal in phase 2 is not negligible.…
0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters Replied, post #102 · Devices › Syringes & needles · 11 Jul 2026 · 3 likes U-100 means the barrel is graduated for a solution containing one hundred units of insulin per millilitre. For anything that is not insulin, the units are simply…
How shortages have affected compounding permissions Replied, post #15 · Access › Shortages · 4 Jul 2026 · 24 likes Narrowing post #14, because the general version has more than one answer. Anyone reporting availability should say the region and the date, because both determine…
Personal or family history of medullary thyroid carcinoma Replied, post #36 · Safety › Contraindications · 1 Jul 2026 · 0 likes Allergy to the specific compound: true allergy is rare but possible. Any prior allergic reaction to the same compound or to structurally similar peptides warrants…
Named, unnamed and unspecified impurities as regulatory categories — the long version Replied, post #38 · Analytics › Impurities & related substances · 1 Jul 2026 · 0 likes Post #36 and I disagree about the size of the effect, not about the direction. Freeze-drying itself does not generate impurities in any significant way. Handling before…
Why the absence of controlled human data on BPC-157 matters more than people admit Replied, post #47 · Compounds › Repair & healing peptides · 23 Jun 2026 · 12 likes What would change the position on repair peptides: adequately powered, published, peer-reviewed randomised controlled human trials with pre-specified outcomes. That is…
What a certificate commits its issuer to — one year on Replied, post #93 · Analytics › COA interpretation · 21 Jun 2026 · 32 likes Where I part company with post #89, and it is a narrow parting. An itemised related-substances table with retention times says considerably more about the synthesis…
HbA1c lag and what it can and cannot tell you at eight weeks — one year on Replied, post #12 · Clinical › Bloodwork · 19 Jun 2026 · 0 likes Seconded. It reads as careful rather than confident, which is the right register.
An appeal that succeeded, with the letter structure — the long version Replied, post #50 · Access › Insurance & coverage · 4 Jun 2026 · 2 likes Reimbursement changes: a compound covered one year might not be the next. A formulary decision in January can change by April. Checking again before refilling saves…