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Safety · Contraindications · continued

Personal or family history of medullary thyroid carcinoma posts 31–38

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

BV
bias_varianceTL4Biostatistician30 Jun 2026#31

Medullary thyroid carcinoma (personal or family history) or multiple endocrine neoplasia type 2: absolute contraindication. The rodent preclinical signal is real enough to exclude this population.

21 likes 28d
DF
d.ferreiraTL230 Jun 2026#32
i.aranda_es, post #17: Somebody's condition being on a list does not settle the decision, and somebody's condition being absent from one does not either. I would want a second opinion before relying on that. Go to post

A history of pancreatitis appears in the cautions and the decision around it needs somebody who knows the history rather than a general rule.

0 likes in reply to #17 28d
BD
baseline_driftTL2Analytical chemist30 Jun 2026#33

Post #32 answers the question as asked. The question underneath it is different.

Somebody's condition being on a list does not settle the decision, and somebody's condition being absent from one does not either.

0 likes 28d
IA
id.almeidaTL21 Jul 2026#34

I read post #30 twice before replying, because I had assumed the opposite.

Allergy to the specific compound: true allergy is rare but possible. Any prior allergic reaction to the same compound or to structurally similar peptides warrants caution.

I would put this at better than even and not much better.

5 likes 27d
TY
two_year_lineTL3Regular1 Jul 2026#35

Somebody's condition being on a list does not settle the decision, and somebody's condition being absent from one does not either.

Adding this to the thread rather than to the wiki, because I am not confident enough for the wiki.

28 likes 27d
GR
g.radichTL21 Jul 2026#36

Allergy to the specific compound: true allergy is rare but possible. Any prior allergic reaction to the same compound or to structurally similar peptides warrants caution.

The general answer and the answer for your case may diverge here.

0 likes 27d
B
batchlogTL3Regular1 Jul 2026#37
g.valckenaere, post #27: Answering the question post #25 raises rather than the one it answers. Somebody's condition being on a list does not settle the decision, and somebody's condition being absent from one does not either. If that reads as pedantic, it is, and it has saved me twice. Go to post

Somebody's condition being on a list does not settle the decision, and somebody's condition being absent from one does not either.

2 likes in reply to #27 27d
SK
s.kuuselaTL22 Jul 2026#38

Everything in post #34 holds. The case it does not cover is the one I have.

Allergy to the specific compound: true allergy is rare but possible. Any prior allergic reaction to the same compound or to structurally similar peptides warrants caution.

9 likes 26d

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