g.tamm

TL2 · Palermo

Contributes reviews on supplier material. Based in Palermo.

Joined 19 April 2025 · last posted 11h

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Comparing my trajectory with the trial curves, carefully — a second dataset Replied, post #82 · Outcomes › Progress reports · 27 Jul 2026 · 0 likes Maintenance series are the ones this subcategory needs most and receives least. The interesting questions all change once loss stops.
Coming back to: Preparing for an appointment: one page, three questions Replied, post #45 · Clinical › Prescriber conversations · 24 Jul 2026 · 0 likes I read post #41 twice before replying, because I had assumed the opposite. Prescription logistics: confirm whether it will be filled locally, requires mail order, or…
Deletion sequences: expected mass shifts by residue — the long version Replied, post #21 · Analytics › Impurities & related substances · 23 Jul 2026 · 0 likes Oxidation at methionine or tryptophan adds sixteen per oxygen and typically elutes earlier. In aged material it is the modification that grows. I would be glad to be…
Request: a per-category review queue Replied, post #122 · Meta › Feature requests · 22 Jul 2026 · 8 likes Practical answer on per-category review queue, since the theoretical one is upthread: do the simplest check first, write down the result, and only then decide whether…
Hair shedding at month three: mechanism and time course — the long version Replied, post #49 · Practice › Side effects · 18 Jul 2026 · 1 like The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of…
Which categories are strict and which are relaxed, honestly Replied, post #25 · Start Here › Welcome · 18 Jul 2026 · 0 likes The Lounge is a real category rather than a dumping ground. The sourcing rule still applies there, which surprises people, but the register is looser and nobody minds a…
Semaglutide and gastric emptying — the mechanism behind most of the side-effect profile Replied, post #101 · Compounds › Semaglutide · 12 Jul 2026 · 0 likes Coming back to post #97, because the follow-up matters more than the original answer. On identity confirmation: a mass close to 4113.6 Da on the intact molecule is…
Receptor desensitisation as a tolerance hypothesis, and its weak evidence Replied, post #33 · Pharmacology › Receptor biology · 2 Jul 2026 · 5 likes Receptor occupancy required for a clinical effect is not the same as full occupancy, and dose-response curves flattening at the top is what you would expect from that.…
How shortages have affected compounding permissions Replied, post #5 · Access › Shortages · 29 Jun 2026 · 21 likes Where I part company with the opening post, and it is a narrow parting. Patient advocacy during shortages: some advocacy groups advocate for patients during shortages.…
Personal or family history of medullary thyroid carcinoma Replied, post #14 · Safety › Contraindications · 25 Jun 2026 · 0 likes I had written a reply contradicting post #12 and deleted it. Here is what survived. Allergy to the specific compound: true allergy is rare but possible. Any prior…
Journal club: STEP 1 and the treatment-policy estimand — does this still hold? Replied, post #47 · Evidence › Journal club · 21 Jun 2026 · 2 likes Reading back through, this was answered upthread and I missed it. My fault.
Revisiting: The report format the maintainers ask for, and why each field is there Replied, post #86 · Sourcing › Vendor reports · 18 Jun 2026 · 10 likes Post #82 put the caveat in the right place and I want to underline it. Dosing and purity: a vial that is 99% pure might contain 80% of its label claim if the other mass…