Sharps containers are a legal requirement for disposal in several jurisdictions and a sensible precaution everywhere. A rigid sealed container is the minimum.
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Devices · Syringes & needles · continued
0.3 mL versus 0.5 mL versus 1 mL barrels: resolution matters posts 31–60
This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.
Coming back to post #28, because the follow-up matters more than the original answer.
U-100 means the barrel is graduated for a solution containing one hundred units of insulin per millilitre. For anything that is not insulin, the units are simply hundredths of a millilitre.
Reporting the observation and leaving the explanation open deliberately.
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chromatogram, post #23: Post #19 and I disagree about the size of the effect, not about the direction. A detachable luer needle plus hub can retain enough volume to matter. Whether it matters to you depends on your dose, and the arithmetic is worth doing once. That is the honest state of it as of this week. Go to post
Checked the 0.3 ml versus 0.5 ml claim against the primary source this morning. It survives, with a narrower scope than the version quoted here. Posting the narrower scope.
Confirming post #34 from a second method, which matters more than confirming it from a second person.
Sharps containers are a legal requirement for disposal in several jurisdictions and a sensible precaution everywhere. A rigid sealed container is the minimum.
That is where I would start, not where I would stop.
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endo_fellow_rk, post #21: On 0.3 ml versus 0.5 ml, I would rather understate and be corrected upward than overstate and be quoted. That is a house style here and it is a good one. Go to post
I had written a reply contradicting post #32 and deleted it. Here is what survived.
0.3 ml versus 0.5 ml came up in a thread eighteen months ago and was answered well. I cannot find it, which is itself the problem, so here is the reconstruction.
l.vukovic, post #30: Confirming post #27 from a second method, which matters more than confirming it from a second person. I would be cautious about generalising from the 0.3 ml versus 0.5 ml example above. It is a good example. It is one example. Go to post
I will take the caveat as seriously as the claim, which is the point of putting it there.
Adding a small correction to the 0.3 ml versus 0.5 ml summary above rather than a disagreement with it. The substance holds; one of the figures is out by a factor that matters.
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Syringe barrel size: common sizes are 0.3 mL, 0.5 mL, and 1.0 mL. Smaller barrels are more legible for small doses. Larger barrels hold larger volumes. Choose based on your dose.
That distinction has done more work for me than anything else in this category.
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Post #41 describes the usual case. This is about the unusual one.
U-100 means the barrel is graduated for a solution containing one hundred units of insulin per millilitre. For anything that is not insulin, the units are simply hundredths of a millilitre.
The disagreement above is smaller than it looks once the terms are fixed.
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r.sobczak, post #14: The most useful reply I ever got about 0.3 ml versus 0.5 ml was a request to state my units. It sounds like pedantry and it has saved me twice. Go to post
Adding the measurement that post #41 says would settle it.
What I want from this 0.3 ml versus 0.5 ml thread is the list of things that would need to be true for the claim to hold. If we can write that list, we can check it.
Sharps containers are a legal requirement for disposal in several jurisdictions and a sensible precaution everywhere. A rigid sealed container is the minimum.
That is all I can say without guessing.
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l.vukovic, post #30: Confirming post #27 from a second method, which matters more than confirming it from a second person. I would be cautious about generalising from the 0.3 ml versus 0.5 ml example above. It is a good example. It is one example. Go to post
Post #45 describes the usual case. This is about the unusual one.
I have been on both sides of the 0.3 ml versus 0.5 ml argument in this category within eighteen months, which should tell you how strong the evidence for either side is.
ak.kravchenko, post #20: 0.3 ml versus 0.5 ml is a question about a distribution, not about a value, and treating it as a value is what produces the confident wrong answers. Go to post
0.3 ml versus 0.5 ml is a good example of a question where the honest answer is boring and the interesting answers are unsupported. I would go with boring.
Where I part company with post #45, and it is a narrow parting.
U-100 means the barrel is graduated for a solution containing one hundred units of insulin per millilitre. For anything that is not insulin, the units are simply hundredths of a millilitre.
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e.almeida, post #11: Post #8 answers the question as asked. The question underneath it is different. U-100 means the barrel is graduated for a solution containing one hundred units of insulin per millilitre. For anything that is not insulin, the units are simply hundredths of a millilitre. Not a conclusion. A place to stand while looking for one. Go to post
Reading the barrel at eye level matters more than any equipment choice. Parallax at a shallow angle is enough to shift a reading by a graduation.
Worth checking against a second source before it gets quoted onward.
A request rather than an answer: could whoever has the primary source for 0.3 ml versus 0.5 ml post it? I have seen the claim three times this month and each version had lost a qualifier.
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Collapsed as off-topic by two members at trust level 3 or above
Right — I had this wrong and I am glad to have read it before it mattered.
Answering the question post #50 raises rather than the one it answers.
Dead volume: residual liquid in the hub and needle after withdrawal. Typical residual is 0.01 to 0.02 mL for an insulin syringe with a fixed needle. Accounting for it matters if precision matters.
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m.oyelaran, post #7: I had written a reply contradicting post #3 and deleted it. Here is what survived. Whatever the answer on 0.3 ml versus 0.5 ml turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, invite the correction. Go to post
Building on post #52 rather than restating it.
Sharps containers are a legal requirement for disposal in several jurisdictions and a sensible precaution everywhere. A rigid sealed container is the minimum.
That is all the detail I have. Someone else will have more.
Graduation spacing is worth checking before you buy rather than after. Some 1 mL barrels are marked every two units and some every one, and that changes what doses you can read.
Someone will know this better than I do and I hope they say so.
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Source for the 0.3 ml versus 0.5 ml figure, since it was asked for. It is in the discussion rather than the abstract, which is why the version circulating is stronger than the paper is.
Reading the surrounding paragraph is worth the two minutes. The authors are more careful than their summarisers.
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t.abubakar, post #51: Reading the barrel at eye level matters more than any equipment choice. Parallax at a shallow angle is enough to shift a reading by a graduation. Worth checking against a second source before it gets quoted onward. Go to post
I disagree with the framing of 0.3 ml versus 0.5 ml above, and I think it is a substantive disagreement rather than a terminological one. Setting out why, so it can be checked.
The reasoning depends on an assumption that is doing a lot of work and is never stated. If the assumption holds, the conclusion follows. I do not think it holds generally.
Taking post #56 at face value and following it one step further.
U-100 means the barrel is graduated for a solution containing one hundred units of insulin per millilitre. For anything that is not insulin, the units are simply hundredths of a millilitre.
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Post #58 and I disagree about the size of the effect, not about the direction.
Sharps containers are a legal requirement for disposal in several jurisdictions and a sensible precaution everywhere. A rigid sealed container is the minimum.
Anyone with a larger sample, please post it.
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