Lipid changes during rapid weight loss: the expected trajectory Writing it up because I had to work it out twice and would rather nobody else did.
Lipid changes during rapid weight keeps being re-asked here and I think that is because the answer is conditional and the conditions never travel with it.
Attempting to write the conditional version down properly. Corrections welcome and expected — I would like this to end up as a maintained page rather than a fifth thread.
Lipid panel interpretation: total, LDL, HDL, triglycerides all on one panel. Reading them together is more informative than reading one value in isolation. An elevated triglyceride with low HDL is different from triglyceride elevation alone.
Worth separating two things that post #12 runs together.
Time of day: some biomarkers vary across the day. Cortisol in the morning differs from cortisol in the evening. Comparing results from different times of day is comparing things that are not the same.
Adding the boring version of Lipid changes during rapid weight, because the interesting version keeps getting posted and the boring one is usually right.
Check the ordinary explanations, in order, and stop when one of them accounts for what you are seeing. Most of the time the second one does.
Liver enzyme changes during rapid weight loss are commonly reported and have several possible explanations, which is exactly why they need clinical interpretation rather than forum interpretation.
If that is already documented somewhere, ignore me and link it.
On Lipid changes during rapid weight, the part that usually goes wrong is that the question is asked as though it has one answer. It has a range, and the width of the range is the interesting bit.
If you can post the two or three numbers you are working from, several people here will check the arithmetic rather than argue about the conclusion.
Lipid changes during substantial weight loss are expected and their trajectory is not always monotonic. A single mid-course panel can be misleading.
Not disagreeing with anyone above, just adding the bit I keep having to look up.
Read the full topic (57 posts)
| Topic | Participants | Replies | Views | Activity |
|---|---|---|---|---|
|
Second pass at: Fasting versus non-fasting and which tests care
On the subject in the title: Second pass at: Fasting versus non-fasting and which tests care Working notes rather than a conclusion. Posting a small dataset on Fasting versus non-fasting. It is mine, it is…
|
+20 | 25 | 21k | 3mo |
|
HbA1c lag and what it can and cannot tell you at eight weeks
HbA1c lag and what it can and cannot tell you at eight weeks Writing it up because I had to work it out twice and would rather nobody else did. Something about hba1c lag does not reconcile and I would like a…
|
+14 | 18 | 2.6k | 14mo |
|
A single out-of-range value on an otherwise normal panel
Posting this under the heading it deserves: A single out-of-range value on an otherwise normal panel Everything below is what sits behind that. General question, not a request for advice about my own care — I…
|
+70 | 75 | 20k | 6d |
|
Micronutrient status when intake falls substantially — a second dataset
Micronutrient status when intake falls substantially — a second dataset Writing it up because I had to work it out twice and would rather nobody else did. Posting a small dataset on Micronutrient status. It…
|
+9 | 13 | 274 | 14mo |
|
Biological variation versus analytical imprecision — does this still hold?
The question in the title: Biological variation versus analytical imprecision — does this still hold? I will give what I have already checked below so nobody repeats it. The question about Biological…
|
2 | 1.8k | 8mo |
| Topic | Participants | Replies | Views | Activity |
|---|---|---|---|---|
|
Second pass at: Fasting versus non-fasting and which tests care
On the subject in the title: Second pass at: Fasting versus non-fasting and which tests care Working notes rather than a conclusion. Posting a small dataset on Fasting versus non-fasting. It is mine, it is…
|
+20 | 25 | 21k | 3mo |
|
About the Bloodwork category
Panels, reference intervals, biological variation, and resisting the urge to over-read one result. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded…
|
+4 | 8 | 4.4k | 3mo |
|
Biological variation versus analytical imprecision — does this still hold?
The question in the title: Biological variation versus analytical imprecision — does this still hold? I will give what I have already checked below so nobody repeats it. The question about Biological…
|
2 | 1.8k | 8mo | |
|
Lipid changes during rapid weight loss: the expected trajectory
Posting this under the heading it deserves: Lipid changes during rapid weight loss: the expected trajectory Everything below is what sits behind that. Lipid changes during rapid weight: what I expected, what…
|
+11 | 15 | 34k | 11h |
|
Biological variation versus analytical imprecision
On the subject in the title: Biological variation versus analytical imprecision Working notes rather than a conclusion. A question about biological variation versus analytical imprecision that I think has a…
|
2 | 42k | 12mo |