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Topic summary

A ten-fold dose error caught before injection — one year on

This is a generated summary. It shows the 9 most-liked posts from a topic of 158, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.
MM
m.mwangiTL21 Aug 2025#15
ni.stanescu, post #8: Second this, and I would have said it less carefully. Go to post

What would change my mind on ten-fold dose error caught is a second dataset collected by someone with no stake in the first. Until then I hold it loosely and I would rather say so than pretend to more.

32 likes in reply to #8 12mo
RZ
ro.zielinskiTL21 Aug 2025#24

Drawing through a wider needle and injecting through a thinner one is a reasonable approach for a viscous preparation and pointless for an aqueous one.

I am reporting what happened, not recommending it.

30 likes 12mo
HO
h.oyelowoTL2Regular1 Aug 2025#32
m.radich, post #31: Graduation spacing is worth checking before you buy rather than after. Some 1 mL barrels are marked every two units and some every one, and that changes what doses you can read. It is worth stating the boring hypothesis before the interesting one. Go to post

Needle length for subcutaneous delivery is a question about tissue depth and injection angle together. Short needles at ninety degrees and longer ones at an angle reach comparable depths.

Somebody will have a better source than mine, and I hope they post it.

28 likes in reply to #31 12mo
CT
cannula_traceTL3Regular2 Aug 2025#48

The thing about ten-fold dose error caught that took me longest to accept is that a plausible mechanism is not evidence of an effect. It is a reason to look, not a result.

27 likes 12mo
W
WickramasingheTL2Member3 Aug 2025#63

Sharps containers are a legal requirement for disposal in several jurisdictions and a sensible precaution everywhere. A rigid sealed container is the minimum.

27 likes 12mo
BI
blank_injectionTL2Analytical chemist3 Aug 2025#80
ambient_review, post #5: Narrowing post #2, because the general version has more than one answer. Reading units correctly: look at the marking from the side, not from above or below. The bottom of the plunger tip is the reading. Parallax error (wrong angle) is a source of dosing error. Go to post

Post #78 is the version of this I will quote in future. One addition.

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

I would hold that lightly until someone with a larger sample weighs in.

27 likes in reply to #5 12mo
DW
diluent_watchTL2Member3 Aug 2025#86

On post #85 — agreed on the reasoning, with one qualification.

I have three months of notes on ten-fold dose error caught and the honest summary is that the trend is real and the week-to-week numbers are noise. I nearly drew the opposite conclusion from the first fortnight.

28 likes 12mo
AP
a.pereiraTL23 Aug 2025#96

Graduation spacing is worth checking before you buy rather than after. Some 1 mL barrels are marked every two units and some every one, and that changes what doses you can read.

32 likes 12mo
MA
m.adeyemiTL24 Aug 2025#132

Everything in post #130 holds. The case it does not cover is the one I have.

Buying a box of the wrong barrel size is the most common regret described in this subcategory, and the reason is nearly always that the dose was decided after the syringes.

Reporting the observation and leaving the explanation open deliberately.

28 likes 12mo

Read the full topic (158 posts)

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