Practice · Administration

Bleeding at the injection site: normal, and what to do about it

Practice › Administration injection site reaction aseptic technique subcutaneous injection injection site rotation

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Solved by h.eriksen in post #3

On the opening post — agreed on the reasoning, with one qualification. Angle of injection: 90 degrees into pinched tissue ensures subcutaneous placement. It is not always necessary and shallower angles can work, but 90 degrees into a small pinch is the safest technique to learn first. Correct me on the arithmetic if…

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q.zhao_qaTL3Quality assurance10 Sep 2025#1

Bleeding at the injection site: normal, and what to do about it — setting out what I have, and where I think it stops being reliable.

Something changed and I would like to know whether it should have.

Same compound, same supplier, same technique, 3 weeks apart, and the experience is not the same. I have ruled out the obvious differences and I am left with the ones I cannot rule out from here.

Before anyone suggests it: yes, I have the dates written down, and yes, I checked them rather than remembering them.

26 likes 11mo

c.lundgrenTL211 Oct 2025#2

Site reactions that appear immediately and settle within a day are described commonly here. Ones that appear a day later and spread are a different observation and worth describing to a clinician rather than a forum.

If the premise is wrong, everything after it is decoration.

5 likes 10mo

h.eriksenTL2 Solution2 Nov 2025#3

q.zhao_qa, post #1: Bleeding at the injection site: normal, and what to do about it — setting out what I have, and where I think it stops being reliable. Something changed and I would like to know whether it should have. Same compound, same supplier, same technique, 3 weeks apart, and the experience is not the same. I have ruled out the obvious differences… Go to post

On the opening post — agreed on the reasoning, with one qualification.

Angle of injection: 90 degrees into pinched tissue ensures subcutaneous placement. It is not always necessary and shallower angles can work, but 90 degrees into a small pinch is the safest technique to learn first.

Correct me on the arithmetic if it is wrong; I would rather know.

7 likes in reply to #1 9mo

z.laurentTL222 Nov 2025#4

Picking up post #3: that is the part I would want checked first.

Drawing up with one needle and injecting with another: a reasonable practice if you have extra needles. Fresh needle for injection reduces tissue drag and can decrease discomfort. Not necessary, but not harmful either.

0 likes 8mo

This topic was referenced in

Injection discomfort: needle gauge, volume, temperature, technique — one year onPractice › Administration · 2 replies

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