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Topic summary

Documenting a supplier's response to a discrepancy — does this still hold?

This is a generated summary. It shows the 8 most-liked posts from a topic of 53, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.
FN
formulary_notesTL3Regular18 Mar 2025 · edited#4

Dosing and purity: a vial that is 99% pure might contain 80% of its label claim if the other mass is water, counter-ion, and excipient. Purity and content are different. Both matter for different reasons.

25 likes 16mo
RW
r.weissTL220 Mar 2025#9

Pattern across lots: a single result is a data point. Three or four results from the same supplier showing a consistent pattern becomes a record worth discussing. Two results that disagree might just be measurement variation.

It is one reading of the data and not the only reasonable one.

24 likes 16mo
FD
f.danquahTL221 Mar 2025#11
r.weiss, post #9: Pattern across lots: a single result is a data point. Three or four results from the same supplier showing a consistent pattern becomes a record worth discussing. Two results that disagree might just be measurement variation. It is one reading of the data and not the only reasonable one. Go to post

Dosing and purity: a vial that is 99% pure might contain 80% of its label claim if the other mass is water, counter-ion, and excipient. Purity and content are different. Both matter for different reasons.

Someone should write this up properly, and it should probably not be me.

28 likes in reply to #9 16mo
DM
d.magalhesTL2Member29 Mar 2025#33

What "verified" means on our pages: specific lots were independently measured on stated dates by named services and results were consistent with the supplier's documentation. It is not a recommendation and does not extend to untested lots.

30 likes 16mo
D
DSakamotoTL3Regular30 Mar 2025#37

Date the report: when the analysis was done matters. Material can degrade in storage. A report from two years ago is still useful but is not evidence about the current state of the same supplier's stock.

A single observation, in a thread that deserves better than single observations.

23 likes 16mo
PO
pe.onwukaTL22 Apr 2025#48
i.ilunga, post #7: Coming back to post #5, because the follow-up matters more than the original answer. Reports of ordinary results are more valuable than reports of remarkable ones, precisely because only the remarkable ones get posted elsewhere. It is worth checking rather than assuming, which costs nothing. Go to post

Reading rather than contributing, but this is the most useful thread I have found on it.

25 likes in reply to #7 16mo
AR
ambient_reviewTL3Regular2 Apr 2025#49

On post #47 — agreed on the reasoning, with one qualification.

Reports of ordinary results are more valuable than reports of remarkable ones, precisely because only the remarkable ones get posted elsewhere.

33 likes 16mo
PT
p.trevinoTL23 Apr 2025#51

Picking up post #50: that is the part I would want checked first.

The cost of a submission is worth stating. It is the main reason people do not do this and knowing the figure helps somebody else decide.

Adding this to the thread rather than to the wiki, because I am not confident enough for the wiki.

26 likes 16mo

Read the full topic (53 posts)

Moved from Payments by j.mwangi. Category placement is not obvious from outside and getting it wrong is expected. This topic will get better answers here. The move is recorded in the public log citing R7.

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