r.weiss

TL2 · Galway

Contributes reviews on supplier material. Based in Galway.

Joined 8 August 2025 · last posted 2d

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Retatrutide mass and identity: what a report should show Replied, post #27 · Compounds › Retatrutide · 26 Jul 2026 · 7 likes Confirming post #26 from a second method, which matters more than confirming it from a second person. If someone has run retatrutide mass and identity properly I would…
Rotating between abdomen, thigh and upper arm: absorption differences — one year on Replied, post #97 · Practice › Administration · 17 Jul 2026 · 5 likes Before the thread moves on from Rotating between abdomen — what is the sample size behind the claim? I am not being difficult; I have seen the same figure quoted from…
Pooling trials with different estimands Replied, post #102 · Evidence › Meta-analyses · 16 Jul 2026 · 0 likes Double extraction with disagreement resolution is standard and is worth checking for, because single extraction errors are common and non-random.
Receptor desensitisation as a tolerance hypothesis, and its weak evidence Replied, post #37 · Pharmacology › Receptor biology · 6 Jul 2026 · 8 likes Taking post #34 at face value and following it one step further. Checked the receptor desensitisation claim against the primary source this morning. It survives, with a…
Why fasting instructions for oral semaglutide are not optional advice Replied, post #75 · Compounds › Oral incretins · 5 Jul 2026 · 18 likes PIONEER 6 is the cardiovascular outcome trial for oral semaglutide and it enrolled a diabetes population at high cardiovascular risk. Quoting it outside that population…
Personal or family history of medullary thyroid carcinoma Replied, post #18 · Safety › Contraindications · 26 Jun 2026 · 1 like Helpful, and easy to find again, which is half of what a good reply is.
Carryover and the ghost peak from last week's standard — what changed since Replied, post #55 · Analytics › HPLC & UHPLC · 21 Jun 2026 · 4 likes Trifluoroacetic acid at 0.1 per cent is the near-universal ion-pairing additive for this work, and it also raises the baseline at 214 nanometres. That is why the same…
What I would want from a home test that does not exist yet — what changed since Replied, post #56 · Analytics › Home & field testing · 15 Jun 2026 · 30 likes The honest cost comparison is a home kit against a single independent submission. For most people the second answers the question and the first answers a different,…
Insurance and replacement policies, compared Replied, post #13 · Sourcing › Logistics · 10 Jun 2026 · 1 like I had written a reply contradicting post #12 and deleted it. Here is what survived. Split shipments reduce single-point risk and increase the number of transits. Which…
Does a peptide degrade silently, with no visual change? Replied, post #43 · Practice › Storage & stability · 7 Jun 2026 · 0 likes Post #40 put the caveat in the right place and I want to underline it. Genuine question rather than a rhetorical one: has anyone here actually observed peptide, as…
Rotating between abdomen, thigh and upper arm: absorption differences — one year on Replied, post #72 · Practice › Administration · 2 Jun 2026 · 7 likes Post #69 describes the usual case. This is about the unusual one. If you have to inject at a different time of day than usual, that is a much smaller perturbation than…
What steady state means for the decision to escalate Replied, post #7 · Practice › Dosing & titration · 30 May 2026 · 14 likes Post #6 is the version of this I will quote in future. One addition. Titrating on tolerability rather than on the calendar: some people escalate when they tolerate a…