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Topic summary

Domestic fridge temperature mapping: a cheap experiment — what changed since

This is a generated summary. It shows the 9 most-liked posts from a topic of 156, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.
NH
n.hartmannTL210 Nov 2024 · edited#8

Narrowing post #7, because the general version has more than one answer.

The version of Domestic fridge temperature mapping that circulates here is a simplification of a simplification. It is not wrong, but it has lost the conditions under which it holds, and those conditions are where the interesting cases live.

29 likes 21mo
GV
g.valckenaereTL3Regular17 Dec 2024#23
p.marchetti, post #16: Post #15 put the caveat in the right place and I want to underline it. Lyophilised material is far more tolerant of a warm transit than a solution would be, which is why suppliers ship dry and why an excursion is not automatically a loss. Go to post

Post #19 describes the usual case. This is about the unusual one.

Two things can be true about Domestic fridge temperature mapping at once: the mechanism is plausible and the evidence for the size of the effect is thin. Most of the argument here is people defending the first against attacks on the second.

30 likes in reply to #16 19mo
HB
h.bhattacharyaTL230 Jan 2025#44

Whatever the answer on Domestic fridge temperature mapping turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, invite the correction.

29 likes 18mo
VS
v.szaboTL3Analytical chemist15 Feb 2025#52

Same experience here, different supplier, so it is at least not unique to one of them.

31 likes 17mo
AW
a.weissTL228 Feb 2025#59

Do not judge cold-chain performance from a single delivery in either direction. It is a distribution and one sample from it is one sample.

Old habit: I write down the expected answer before I calculate it.

29 likes 17mo
DO
d.oyelaranTL3Pharmacist11 Mar 2025#65
st.diallo, post #24: Thank you for taking the time. That was more work than a reply usually is. Go to post

Temperature loggers in the parcel exist and are occasionally used for high-value shipments. They are the only thing that turns an argument about transit into a record.

The number is defensible. The precision I gave it is not.

31 likes in reply to #24 17mo
SK
s.karlsen_rphTL3Pharmacist6 May 2025#98

Where I would push back on the Domestic fridge temperature mapping consensus is the confidence, not the direction. The direction looks right. The confidence is borrowed.

29 likes 15mo
JN
j.nwosuTL222 Jun 2025#128

I had written a reply contradicting post #126 and deleted it. Here is what survived.

Temperature loggers in the parcel exist and are occasionally used for high-value shipments. They are the only thing that turns an argument about transit into a record.

If anyone can point at the primary source I would be grateful.

31 likes 13mo
M
MJayawardenaTL3Regular24 Jun 2025#129

Domestic refrigeration: most lyophilised peptides are stored at 2–8 °C (35–46 °F). That is standard refrigerator temperature. Check your refrigerator's actual temperature; some are warmer than the label.

I have written this out at length because the short version keeps being misread.

33 likes 13mo

Read the full topic (156 posts)

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