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Regional · North America · continued

Follow-up: State-level differences that actually matter posts 61–90

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

FP
f.piresTL27 Apr 2026#61
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NicolaidesTL3Regular7 Apr 2026#62
h.eriksen, post #29: Everything in post #27 holds. The case it does not cover is the one I have. Distinguishing three things in the State-level differences discussion that keep getting used interchangeably: the observation, the proposed mechanism, and the recommendation that gets attached to both. Go to post

Building on post #59 rather than restating it.

I have been on both sides of the State-level differences argument in this category within eighteen months, which should tell you how strong the evidence for either side is.

12 likes in reply to #29 4mo
WV
w.verhoevenTL27 Apr 2026#63

One caution on State-level differences: everything above assumes the underlying documentation is what it claims to be. That assumption is doing real work and is rarely stated.

1 like 4mo
AL
aliquot_lineTL3Regular7 Apr 2026#64

Nothing in this subcategory is medical or legal advice, and the clinicians posting here say so on their own account.

I would treat the number as indicative rather than as a measurement.

0 likes 4mo
RW
r.weissTL27 Apr 2026#65
s.duarte, post #38: The denial letter is the specification for the appeal. It states a criterion and the job is to demonstrate that criterion in the letter's own language. Happy to expand any of that if it is the useful part. Go to post

Whatever the answer on State-level differences turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, invite the correction.

18 likes in reply to #38 4mo
IA
i.aranda_esTL2Translator · ES7 Apr 2026 · edited#66

On State-level differences, I would rather understate and be corrected upward than overstate and be quoted. That is a house style here and it is a good one.

7 likes 4mo
KM
k.marchandTL27 Apr 2026#67

Everything in post #63 holds. The case it does not cover is the one I have.

Both are useful and different. The account tells you what happens in practice; the criterion tells you what to write.

This is the version I would want a new member to read first.

0 likes 4mo
MH
m.haddadTL2Regular7 Apr 2026#68

The number people quote for State-level differences is a central estimate presented without its interval, and the interval is wide enough that the estimate is nearly uninformative on its own.

0 likes 4mo
AM
a.molnarTL27 Apr 2026#69
f.pires, post #61: This is the answer, and the reason it is the answer is the more useful part. Go to post

Worth separating two things that post #67 runs together.

State-level differences was covered in the wiki last year and the page has a review date on it, which is a better starting point than my memory of a thread.

0 likes in reply to #61 4mo
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DSakamotoTL3Regular7 Apr 2026#70

Bookmarking this. I will come back when I have something worth adding.

24 likes 4mo
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i.almeidaTL27 Apr 2026#71

Taking post #69 at face value and following it one step further.

Appeals succeed more often than people expect when they answer the stated criterion point by point and include nothing else.

2 likes 4mo
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dr_seongTL3Physician7 Apr 2026#72

Speaking only to State-level differences as I have actually seen it, rather than as it is usually described: the effect is real, it is smaller than the thread suggests, and the variance between people is larger than the effect.

9 likes 4mo
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ro.friskTL28 Apr 2026#73

That is a fair summary of where the discussion has got to.

28 likes 4mo
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customs_ledgerTL3Regular8 Apr 2026#74
a.salcedo, post #36: Post #32 and I disagree about the size of the effect, not about the direction. I would put moderate confidence on the mainstream reading of State-level differences and no more. That is not scepticism for its own sake; it is where the sourcing actually stops. Go to post

I read post #72 twice before replying, because I had assumed the opposite.

Source for the State-level differences figure, since it was asked for. It is in the discussion rather than the abstract, which is why the version circulating is stronger than the paper is.

Reading the surrounding paragraph is worth the two minutes. The authors are more careful than their summarisers.

0 likes in reply to #36 4mo
JF
j.fonsecaTL28 Apr 2026#75
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PharmNotes_WhitfieldTL4Pharmacist8 Apr 2026 · edited#76

Post #72 put the caveat in the right place and I want to underline it.

Two claims get bundled together under State-level differences and they need separating. The descriptive one — this is what was observed — is usually well supported. The causal one — this is why — usually is not.

Almost every disagreement in threads like this one dissolves once you say which of the two you are making.

13 likes 4mo
NB
n.brobergTL28 Apr 2026#77

I changed my mind about State-level differences after someone here asked me for the source and I could not produce one. That is worth saying out loud because it is the ordinary way it happens.

0 likes 4mo
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orbitrap_olaTL3Mass spectrometrist8 Apr 2026#78

Date every claim in this subcategory. Positions here have moved repeatedly and old posts are read as current.

Caveat: everything above assumes the paperwork is what it says it is.

0 likes 4mo
HE
h.espinozaTL28 Apr 2026#79
Norrington, post #2: If you are new and reading this thread for the answer to State-level differences: the answer is conditional, the conditions are in the third reply, and the rest of the thread is worth skipping. Go to post

A note on scope: what I am saying about State-level differences applies to the case in the first post and I would not extend it further without checking.

0 likes in reply to #2 4mo
YM
y.mensahTL3Wiki editor8 Apr 2026#80

On post #76 — agreed on the reasoning, with one qualification.

State-level differences has been discussed here with more heat than it deserves, mostly because two definitions have been in play the whole time.

2 likes 4mo
LP
l.piresTL28 Apr 2026#81
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a.asanteTL28 Apr 2026#82

Adding the measurement that post #80 says would settle it.

I keep a log for State-level differences specifically because my memory of it turned out to be systematically wrong in one direction. Six weeks of notes cost nothing and settled it.

11 likes 4mo
LS
l.solbergTL28 Apr 2026#83

Adding the boring version of State-level differences, because the interesting version keeps getting posted and the boring one is usually right.

Check the ordinary explanations, in order, and stop when one of them accounts for what you are seeing. Most of the time the second one does.

3 likes 4mo
HM
h.mensahTL28 Apr 2026#84
n.broberg, post #77: I changed my mind about State-level differences after someone here asked me for the source and I could not produce one. That is worth saying out loud because it is the ordinary way it happens. Go to post

Cross-border purchasing raises both a legal question and a practical one, and the legal one is yours to establish for your own jurisdiction.

This is where my knowledge stops and I would rather mark the edge than blur it.

0 likes in reply to #77 4mo
RL
r.laurentTL28 Apr 2026 · edited#85
KLindqvist, post #50: Post #49 answers the question as asked. The question underneath it is different. Adding what did not work for me on State-level differences, since the failures never get written up and they are half the useful information. Go to post

Small correction to my own earlier position on State-level differences. I had the units the wrong way round, which changes the conclusion by an order of magnitude and therefore changes it entirely.

18 likes in reply to #50 4mo
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e.verhoevenTL28 Apr 2026#86

Picking up post #85: that is the part I would want checked first.

The confident answers on State-level differences and the well-sourced answers are not the same answers, which is the most useful thing I have learned reading this category.

7 likes 4mo
MO
m.onwukaTL28 Apr 2026#87

No notes. Posting so the count is not one.

1 like 4mo
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mira.patelTL4 Admin8 Apr 2026#88

Prior authorisation criteria are usually published by the payer and reading them before the appointment changes the outcome more than anything else does.

I would want a second opinion before relying on that.

0 likes 4mo
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taper_shiftTL3Regular8 Apr 2026#89
y.mensah, post #80: On post #76 — agreed on the reasoning, with one qualification. State-level differences has been discussed here with more heat than it deserves, mostly because two definitions have been in play the whole time. Go to post

Private insurance gaps: some people have private insurance but medication is not covered. Manufacturer assistance programmes are the main resource for cost reduction.

It reads as pedantry until the day it does not.

0 likes in reply to #80 4mo
JC
j.cabreraTL28 Apr 2026#90