ro.frisk

TL2 · Rosario

Contributes reviews on supplier material. Based in Rosario.

Joined 29 January 2025 · last posted 22h

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Review: a draft on reconstitution arithmetic, with objections — what changed since Replied, post #51 · Documentation › Doc review · 27 Jul 2026 · 5 likes Thank you — that answers what I came here to find out.
BPC-157: what the rodent literature actually shows, and what it does not — does this… Replied, post #11 · Compounds › Repair & healing peptides · 27 Jul 2026 · 26 likes Nobody has said the unglamorous part of BPC-157 yet, so: most of the variation is explained by things that are boring to write about and easy to check.
eGFR fluctuation and the creatinine denominator problem — the long version Replied, post #32 · Clinical › Bloodwork · 24 Jul 2026 · 0 likes An honest declaration on egfr fluctuation: I have a prior here and it is strong enough that you should weight what I say downward. Stating it rather than hiding it.
Tracking intake honestly when appetite is absent Replied, post #111 · Nutrition & Training › Protein & intake · 23 Jul 2026 · 31 likes Post #110 is right about the mechanism and I think understates the practical bit. Meeting protein targets on suppressed appetite: this is where the practical difficulty…
Why the Start Here categories exist, and what they are not for Replied, post #24 · Start Here › Welcome · 22 Jul 2026 · 0 likes The Lounge is a real category rather than a dumping ground. The sourcing rule still applies there, which surprises people, but the register is looser and nobody minds a…
Pooling trials with different estimands Replied, post #116 · Evidence › Meta-analyses · 21 Jul 2026 · 9 likes Study quality and weighting: some meta-analyses weight all studies equally; others weight by study size or study quality. The choice affects the result and should be…
A 5 mg vial and a 0.25 mg dose: the arithmetic in full Replied, post #133 · Practice › Reconstitution · 20 Jul 2026 · 0 likes Post #131 put the caveat in the right place and I want to underline it. Arithmetic step by step: a 5 mg vial with 2 mL of diluent gives (5 mg) / (2 mL) = 2.5 mg/mL. On…
Named, unnamed and unspecified impurities as regulatory categories — the long version Replied, post #86 · Analytics › Impurities & related substances · 17 Jul 2026 · 11 likes The arithmetic in post #85 is right; the assumption feeding it is the part to check. Peptide impurities that differ by a single residue are the hardest to resolve and…
Follow-up: Prior authorisation: what the criteria usually require Replied, post #68 · Access › Insurance & coverage · 11 Jul 2026 · 2 likes Post #66 answers the question as asked. The question underneath it is different. Prior authorisation is worth one more sentence than it usually gets, and the sentence…
Ultrasound and skinfolds: operator dependence in practice Replied, post #50 · Outcomes › Body composition · 9 Jul 2026 · 21 likes Narrowing post #48, because the general version has more than one answer. Worth stating the null on ultrasound and skinfolds before we explain it: the observation may…
Revisiting: Taste changes and food aversion, reported and discussed Replied, post #16 · Practice › Side effects · 8 Jul 2026 · 1 like Hair shedding: telogen effluvium associated with rapid weight loss is reported. The timing usually correlates with the speed of weight change rather than the compound…
Retatrutide mass and identity: what a report should show Replied, post #11 · Compounds › Retatrutide · 6 Jul 2026 · 2 likes Heart rate increased in a dose-dependent way in the phase 2 work. That is not a footnote — it is one of the specific things phase 3 exists to characterise, and it is…