Where the Pinch reasoning breaks down for me is the step from the group result to the individual case. That step is almost never argued for.
Pinch or no pinch, and how needle length changes the answer — the long version
I have no financial interest in anything named in this thread and I want to say so before I comment on Pinch, because it is the sort of subject where it matters.
Nothing in this subcategory is medical advice and none of it is a substitute for a demonstration from somebody qualified to give one, which most prescribers will do without being asked twice.
Adding a source would improve this post and I do not have one to hand.
A new needle for each injection is not fussiness. A needle blunts on first use and a blunted needle is the reason the second injection hurts more than the first.
Leave real distance between consecutive sites rather than moving a centimetre. Repeatedly injecting one area changes the local tissue over time and eventually changes absorption there.
I have three months of notes on Pinch and the honest summary is that the trend is real and the week-to-week numbers are noise. I nearly drew the opposite conclusion from the first fortnight.
The version of Pinch that circulates here is a simplification of a simplification. It is not wrong, but it has lost the conditions under which it holds, and those conditions are where the interesting cases live.
The practical version of Pinch is three sentences long. The rigorous version is three pages and reaches the same conclusion with the conditions attached.
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