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Practice · Side effects · continued

Taste changes and food aversion, reported and discussed posts 31–48

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1 · go to the accepted answer.

NS
n.stanescuTL219 Oct 2024#31
f.fenwick, post #29: Narrowing post #26, because the general version has more than one answer. Taste changes and food aversion has a well-known answer and a correct answer, and the interesting work is establishing that they are the same. Nobody has done that here yet. Go to post

The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of an inactive preparation.

19 likes in reply to #29 21mo
JN
j.nwosuTL222 Oct 2024#32
gradient_file, post #23: This follows post #21 rather than contradicting it. A definition problem is doing most of the work in this taste changes and food aversion discussion. Once the term is pinned down I suspect the disagreement mostly goes away and what is left is small. Go to post

The failure mode on taste changes and food aversion is boring rather than dramatic. It is almost always the step everyone assumes was done correctly because it is too simple to get wrong.

8 likes in reply to #23 21mo
SK
s.kimaniTL225 Oct 2024#33

Adding a reference point for taste changes and food aversion. Mine is a single case, collected without controls, and I am posting the method alongside it so it can be discounted appropriately.

0 likes 21mo
NH
n.haddadTL228 Oct 2024#34
DE
d.eriksenTL230 Oct 2024#35

What I can speak to on taste changes and food aversion is narrow, so I will keep it narrow rather than generalising from it. Beyond that boundary I do not know.

26 likes 21mo
JM
j.mwangiTL4 Moderator2 Nov 2024 · edited#36
f.fenwick, post #29: Narrowing post #26, because the general version has more than one answer. Taste changes and food aversion has a well-known answer and a correct answer, and the interesting work is establishing that they are the same. Nobody has done that here yet. Go to post

Summarising the taste changes and food aversion thread so far, since it is long and the answer is buried: the first reply has the method, the fourth has the correction to it, and the rest is people agreeing at length.

12 likes in reply to #29 21mo
BV
b.vanheckeTL25 Nov 2024#37

Good question, well framed, and I would like to see it answered properly.

2 likes 21mo
MS
m.strand_rphTL3Pharmacist8 Nov 2024#38

Building on post #35 rather than restating it.

The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of an inactive preparation.

Adding it because I spent an afternoon working it out and nobody should have to twice.

0 likes 21mo
VK
v.klausenTL3Regular10 Nov 2024#39
VPoulsen, post #6: Filing a mild objection to the consensus on taste changes and food aversion. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Go to post

A methods point on taste changes and food aversion rather than a substantive one: if the comparison is not like for like, the difference you are measuring is the difference in method.

0 likes in reply to #6 21mo
EC
e.coelhoTL213 Nov 2024#40

Adding the measurement that post #39 says would settle it.

Agreed on taste changes and food aversion, with one qualification that I think matters. The reasoning holds for the case as described. Change the starting assumption and it does not, and the starting assumption is the part nobody states.

18 likes 20mo
BE
bench_entryTL3Regular15 Nov 2024#41

Building on post #40 rather than restating it.

The published rates come from populations that were titrated on a defined schedule with clinical supervision. Rates from a forum are not comparable and are biased by who chooses to post.

Not a conclusion. A place to stand while looking for one.

1 like 20mo
BF
b.friskTL218 Nov 2024#42
BS
buffer_sheetTL3Regular21 Nov 2024#43
ca.vermeulen, post #24: Worth separating two things that post #20 runs together. What I would check first on taste changes and food aversion is whether the thing being measured moved or whether the way of measuring it moved. Those look identical in a graph. Go to post

Answering the taste changes and food aversion question as asked, then the question I think is meant. As asked: yes, with the qualification below. As meant: it depends on how the first measurement was taken.

17 likes in reply to #24 20mo
FL
f.lindholmTL223 Nov 2024#44
n.haddad, post #34: Taking post #31 at face value and following it one step further. Reported effects on taste and on food preference are common and interesting and unstudied in any detail. They are also the ones people find most disconcerting. I would call that likely rather than established. Go to post

Fatigue: commonly reported, frequently multifactorial. It is worth asking whether other factors have changed (sleep, training volume, diet adequacy, hydration) before attributing all of it to the compound. Some fatigue resolves with time; some persists.

33 likes in reply to #34 20mo
CC
crossref_checkTL3Wiki editor26 Nov 2024#45

Post #44 is the version of this I will quote in future. One addition.

Constipation is reported at least as often as nausea and is discussed a fraction as much. Fluid, fibre and movement are the boring answers and they are the ones that work.

The general case is well covered; this is the awkward specific one.

3 likes 20mo
JF
j.falkTL228 Nov 2024#46

Taking taste changes and food aversion seriously for a moment rather than deflecting: the honest position is that the community has observations and no controlled comparison, and those two things support very different sentences.

11 likes 20mo
V
VPoulsenTL3Regular1 Dec 2024#47
n.stanescu, post #31: The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of an inactive preparation. Go to post

The relationship between symptom burden and outcome is not what people assume. Feeling worse is not evidence of a larger effect and feeling nothing is not evidence of an inactive preparation.

24 likes in reply to #31 20mo
IW
i.wojcikTL24 Dec 2024#48

Answering the question post #46 raises rather than the one it answers.

Taste changes and food aversion is well covered in the tag pages, and the older discussions are better than the recent ones because they were argued out properly. Worth twenty minutes before adding to this one.

0 likes 20mo
This topic was closed 60 days after the last reply. Closing is automatic for quiet topics so that a settled answer does not collect new questions underneath it. If you have a follow-up, open a new topic and link back to this one — that keeps both readable and gives your question its own title.

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