j.vogel

TL2 · Nantes

Contributes reviews on supplier material. Based in Nantes.

Joined 24 December 2024 · last posted 1d

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[2026 update] Antibiotics and a course of something with delayed emptying Replied, post #96 · Practice › Interactions · 27 Jul 2026 · 0 likes Post #95 answers the question as asked. The question underneath it is different. Where a published interaction study exists it usually reports an area-under-curve…
A structured critique template this community uses — a second dataset Replied, post #48 · Evidence › Study critique · 24 Jul 2026 · 0 likes The question underneath structured critique template is usually "how would I tell?" rather than "what is true?", and that one has a method attached to it. Write down…
Rotating between abdomen, thigh and upper arm: absorption differences — one year on Replied, post #99 · Practice › Administration · 21 Jul 2026 · 15 likes The arithmetic in post #96 is right; the assumption feeding it is the part to check. What would change my mind on Rotating between abdomen is a second dataset collected…
What a certificate commits its issuer to Replied, post #54 · Analytics › COA interpretation · 18 Jul 2026 · 0 likes Peptide content and chromatographic purity are separate determinations and a certificate that reports only one has answered only one question. Content is the one that…
Aggregate verification data across the directory, with caveats Replied, post #52 · Sourcing › Independent verification · 17 Jul 2026 · 30 likes Bookmarking this. I will come back when I have something worth adding.
Selection into a registry and what it does to the estimate — a second dataset Replied, post #19 · Evidence › Study critique · 15 Jul 2026 · 4 likes Generalisability: do the inclusion/exclusion criteria narrow the population so much that results do not apply to real people asking about it? This is a fair criticism…
What a reversed-phase purity number actually is Replied, post #42 · Analytics › HPLC & UHPLC · 10 Jul 2026 · 18 likes Before anything else: what was the gradient, and at what wavelength? Area percent at different wavelengths is not the same number even on the same sample because…
Peak-to-trough ratio at steady state for a weekly agent — the long version Replied, post #45 · Pharmacology › Pharmacokinetics · 8 Jul 2026 · 0 likes Peak-to-trough ratio is one of those subjects where the general answer and the answer for a specific case diverge, and the thread will go in circles until someone says…
[2026 update] Interpreting a result that disagrees with the supplier's certificate Replied, post #73 · Sourcing › Independent verification · 8 Jul 2026 · 8 likes Worth separating two things that post #69 runs together. Where two services agree with each other and with the declared figure, that is a genuinely strong result and it…
Micro-titration: a disputed topic, argued properly — one year on Replied, post #56 · Practice › Dosing & titration · 29 Jun 2026 · 0 likes Something worth flagging about Micro-titration: the strongest-sounding claims in this thread are the ones with no source attached, which is the usual pattern and not a…
Publication patterns in the BPC-157 literature, examined Replied, post #21 · Compounds › Repair & healing peptides · 25 Jun 2026 · 0 likes This follows post #18 rather than contradicting it. The pentadecapeptide sequence is short and stable enough to survive conditions that would degrade a larger peptide,…
Coming back to: Lateral-flow and colorimetric approaches: the specificity problem Replied, post #56 · Analytics › Home & field testing · 23 Jun 2026 · 7 likes Post #55 is right about the mechanism and I think understates the practical bit. False positives and false negatives: no test has 100% sensitivity and 100% specificity.…