Topic summary

Conditions that change the calculus rather than forbidding it

Safety › Contraindications disordered eating pregnancy & planning pancreatitis delayed gastric emptying

This is a generated summary. It shows the 5 most-liked posts from a topic of 33, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.

r.laurentTL226 Mar 2026 · edited#5

b.fonseca, post #3: Pregnancy appears in the labelling for this class and the position is stated explicitly rather than left to inference. Go to post

Where I part company with the opening post, and it is a narrow parting.

I think the conditions question is answerable and has not been answered, which is a more optimistic position than most of this thread.

26 likes in reply to #3 4mo

taper_shiftTL3Regular16 Apr 2026#9

Where a condition appears as a warning rather than a contraindication, the decision is a clinical one rather than a prohibition.

That is what I would do. It may not be what is correct.

19 likes 3mo

p.iyer_pharmdTL3Pharmacist26 Apr 2026#11

aliquot_line, post #1: Conditions that change the calculus rather than forbidding it Writing it up because I had to work it out twice and would rather nobody else did. What changes if the standard account of conditions is wrong? I ask because I have been treating it as settled and I noticed this week that I could not say why. Working through the consequences… Go to post

A history of pancreatitis appears in the cautions and the decision around it needs somebody who knows the history rather than a general rule.

22 likes in reply to #1 3mo

j.dahlbergTL25 Jun 2026#20

a.asante, post #2: Personal or family history of medullary thyroid carcinoma, or multiple endocrine neoplasia type 2, is the clearest contraindication in this class and it is specific rather than general. I would be interested in a counterexample if anyone has one. Go to post

Allergy to the specific compound: true allergy is rare but possible. Any prior allergic reaction to the same compound or to structurally similar peptides warrants caution.

I would treat the number as indicative rather than as a measurement.

23 likes in reply to #2 2mo

t.kulkarniTL3Regular14 Jun 2026#22

g.oyelaran, post #21: Where labelling has changed, the change is dated and public, and citing the current version is the whole of the discipline. That is all the detail I have. Someone else will have more. Go to post

A history of pancreatitis appears in the cautions and the decision around it needs somebody who knows the history rather than a general rule.

I am describing what is, rather than arguing for what should be.

25 likes in reply to #21 1mo

Read the full topic (33 posts)

This topic was referenced in

Absolute versus relative contraindicationsSafety › Contraindications · 8 replies
Revisiting: Absolute versus relative contraindicationsSafety › Contraindications · 85 replies

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