Topic summary

Fasting versus non-fasting and which tests care

Clinical › Bloodwork eGFR & renal function lipase & amylase HbA1c Solved

This is a generated summary. It shows the 9 most-liked posts from a topic of 79, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.

k.redgraveTL2Member Solution1 Apr 2026#6

j.fonseca, post #1: Fasting versus non-fasting and which tests care Writing it up because I had to work it out twice and would rather nobody else did. Fasting versus non-fasting: what I expected, what I found, and the gap between them. I am posting the gap rather than a theory about it. My theories about gaps like this one have not held up well. Go to post

An observation about fasting versus non-fasting that I cannot explain and am posting anyway, on the principle that unexplained observations are more useful public than private.

8 likes in reply to #1 4mo

a.cabreraTL23 Apr 2026#7

Everything in post #5 holds. The case it does not cover is the one I have.

Glycaemic markers integrate over different periods. A point glucose and a longer-term marker disagreeing is not a contradiction; it is two different questions.

33 likes 4mo

e.kjeldsenTL2Member24 Apr 2026#17

Building on post #14 rather than restating it.

The number people quote for fasting versus non-fasting is a central estimate presented without its interval, and the interval is wide enough that the estimate is nearly uninformative on its own.

30 likes 3mo

hana.satoTL4 Moderator12 May 2026#27

Where I part company with post #25, and it is a narrow parting.

Time of day: some biomarkers vary across the day. Cortisol in the morning differs from cortisol in the evening. Comparing results from different times of day is comparing things that are not the same.

I have separated what I observed from what I concluded, which does not always happen.

25 likes 3mo

dr_bhattacharyaTL3Physician28 May 2026#37

Repeat before acting is standard practice for an isolated abnormal result on most analytes, and it is standard for a reason.

27 likes 2mo

sharps_binTL2Regular8 Jun 2026#44

The arithmetic in post #43 is right; the assumption feeding it is the part to check.

Worth stating the null on fasting versus non-fasting before we explain it: the observation may be nothing. That possibility deserves a sentence and usually does not get one.

26 likes 2mo

journalclub_wrenTL3Regular27 Jun 2026#57

Sensible. I would want the same detail before I acted on it either.

32 likes 1mo

j.mwangiTL4 Moderator5 Jul 2026#63

Posted with less confidence than the sentence structure implies.

31 likes 23d

v.klausenTL3Regular15 Jul 2026 · edited#70

Picking up post #68: that is the part I would want checked first.

An update on my earlier fasting versus non-fasting post: the pattern held for another six weeks and then stopped, which I did not predict and cannot explain.

33 likes 13d

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