Two people in this thread mean different things by gallbladder disease risk and are disagreeing about the definition while believing they are disagreeing about the facts. Worth pausing to define it.
26 likes 23mo
Topic summary
Gallbladder disease risk with rapid weight loss
This is a generated summary. It shows the 9 most-liked posts from a topic of 64, in their original order, with the accepted answer included where one exists. It is a reading aid and it will miss nuance — the full topic is the record.
Cardiovascular disease: several compounds have cardiovascular outcome trials. SELECT was in people without diabetes; SUSTAIN 6 was in high-risk diabetes. Absolute benefit is largest in high-risk people.
It cost nothing to check and would have cost something not to.
25 likes 22mo
Where the gallbladder disease risk discussion usually stalls is that nobody wants to say "I do not know" and everyone is willing to say "it varies". Those are the same sentence with different clothes on.
33 likes 22mo
The bit of gallbladder disease risk that nobody enjoys is that the answer changes depending on what you are trying to decide with it. Say what the decision is and the thread will converge.
33 likes 21mo
resistance_first, post #10: Everything in post #6 holds. The case it does not cover is the one I have. Reading back through the gallbladder disease risk threads from last year, the same three questions come up every time and only one of them has ever been answered properly. That seems like a documentation gap rather than a knowledge gap. Go to post
Narrowing post #26, because the general version has more than one answer.
Gallbladder disease risk came up in a thread eighteen months ago and was answered well. I cannot find it, which is itself the problem, so here is the reconstruction.
Cardiovascular disease: several compounds have cardiovascular outcome trials. SELECT was in people without diabetes; SUSTAIN 6 was in high-risk diabetes. Absolute benefit is largest in high-risk people.
The claim is narrower than it sounds, and deliberately so.
31 likes 20mo
h.amankwah, post #40: Adding the measurement that post #39 says would settle it. Small correction to my own earlier position on gallbladder disease risk. I had the units the wrong way round, which changes the conclusion by an order of magnitude and therefore changes it entirely. Go to post
Interactions between comorbidities: diabetes and kidney disease together change the risk calculation for hypoglycemia and for medication clearance. They are not independent variables.
I have separated what I observed from what I concluded, which does not always happen.
Read the full topic (64 posts)
This topic was referenced in
- Cardiovascular risk: reading the outcome trials as a setClinical › Comorbidities · 4 replies
- Heart failure with preserved ejection fraction: symptom endpointsClinical › Comorbidities · 23 replies
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