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Devices · Syringes & needles · continued

Revisiting: Filter needles: when they help and what they cost you posts 31–53

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

MM
m.marchettiTL226 Jun 2025#31

Needle gauge: smaller numbers (30G) are finer and less painful. Larger numbers (25G) are courser. For subcutaneous injection, 27-30G is typical. Finer needles take longer to draw up but hurt less.

Not disagreeing with anyone above, just adding the bit I keep having to look up.

0 likes 13mo
LS
l.sarkissianTL2Member29 Jun 2025#32
np_gilmore, post #13: Building on post #12 rather than restating it. An update on my earlier Filter needles post: the pattern held for another six weeks and then stopped, which I did not predict and cannot explain. Go to post

I read post #29 twice before replying, because I had assumed the opposite.

If you are new and reading this thread for the answer to Filter needles: the answer is conditional, the conditions are in the third reply, and the rest of the thread is worth skipping.

2 likes in reply to #13 13mo
CN
c.nybergTL23 Jul 2025#33
j.hartmann, post #21: Coring the stopper is a real phenomenon with repeated entries at the same point and blunt needles. Varying the entry point slightly and using a fresh needle prevents it. The confident version of this sentence would be wrong, so here is the hedged one. Go to post

Offering a way to settle Filter needles rather than another opinion about it. Two measurements, taken the same way, a fortnight apart. If the difference is within the noise, the question was not answerable at this precision.

12 likes in reply to #21 13mo
HH
h.hutchingsTL1Member6 Jul 2025#34

U-100 means the barrel is graduated for a solution containing one hundred units of insulin per millilitre. For anything that is not insulin, the units are simply hundredths of a millilitre.

26 likes 13mo
AW
ai.wikstromTL210 Jul 2025#35

That is a cleaner way of putting what I was circling around.

0 likes 13mo
TS
t.steenkampTL2Member13 Jul 2025#36
mira.patel, post #19: The most useful thing anyone has posted about Filter needles in this category was a table of what had been measured and by whom. That is what I would want again. Go to post

Coming back to post #32, because the follow-up matters more than the original answer.

I have three months of notes on Filter needles and the honest summary is that the trend is real and the week-to-week numbers are noise. I nearly drew the opposite conclusion from the first fortnight.

0 likes in reply to #19 13mo
KA
k.adeyemiTL217 Jul 2025#37
i.coelho, post #27: Needle length for subcutaneous delivery is a question about tissue depth and injection angle together. Short needles at ninety degrees and longer ones at an angle reach comparable depths. Go to post

Something worth flagging about Filter needles: the strongest-sounding claims in this thread are the ones with no source attached, which is the usual pattern and not a coincidence.

8 likes in reply to #27 12mo
AD
ambient_draftTL3Regular20 Jul 2025 · edited#38

Safety-engineered needles are worth using if you have children or anyone else in the house, and the retraction mechanism occupies dead volume that ordinary syringes do not.

I have kept the units in throughout, for the obvious reason.

19 likes 12mo
HB
h.brandtTL224 Jul 2025#39

Confirming post #38 from a second method, which matters more than confirming it from a second person.

The documentation on Filter needles is better than this thread and I say that as someone who has posted in the thread.

1 like 12mo
IS
isotonic_sheetTL3Regular27 Jul 2025#40
t.nardone, post #8: Fixed versus detachable needles: insulin syringes usually have fixed needles (no dead volume loss to the hub). Luer-lock syringes use detachable needles (more dead volume). Fixed needles are preferred for small doses. That is what the documentation says. What happens in practice is usually close. Go to post

Sharps containers are a legal requirement for disposal in several jurisdictions and a sensible precaution everywhere. A rigid sealed container is the minimum.

7 likes in reply to #8 12mo
FA
f.amankwahTL230 Jul 2025#41

Post #37 describes the usual case. This is about the unusual one.

Filter needles looks different depending on whether you are reading the primary literature or the summaries of it, and the difference is not in our favour.

0 likes 12mo
BO
b.okonkwoTL23 Aug 2025 · edited#42

Gauge is the outside diameter and higher numbers are thinner. Thinner needles hurt less and draw more slowly, which is the entire trade.

20 likes 12mo
CO
c.ostergaardTL26 Aug 2025#43

Where I would push back on the Filter needles consensus is the confidence, not the direction. The direction looks right. The confidence is borrowed.

8 likes 12mo
HS
hana.satoTL4 Moderator9 Aug 2025#44
j.baptista, post #25: Sharps containers are a legal requirement for disposal in several jurisdictions and a sensible precaution everywhere. A rigid sealed container is the minimum. The mechanism is plausible, which is not the same as established. Go to post

I will take the caveat as seriously as the claim, which is the point of putting it there.

2 likes in reply to #25 12mo
JD
j.dahlbergTL213 Aug 2025#45

U-100 means the barrel is graduated for a solution containing one hundred units of insulin per millilitre. For anything that is not insulin, the units are simply hundredths of a millilitre.

0 likes 11mo
VB
v.bhattacharyaTL216 Aug 2025#46

Careful with the language on Filter needles. "Not detected" and "not present" are different findings and the first is a statement about the method.

27 likes 11mo
FF
f.fonsecaTL219 Aug 2025#47
b.okonkwo, post #42: Gauge is the outside diameter and higher numbers are thinner. Thinner needles hurt less and draw more slowly, which is the entire trade. Go to post

Filter needles are for drawing from glass ampoules where particulate is a real risk. For a stoppered vial they add dead volume in exchange for very little.

Two sources, same conclusion, and I could not rule out that one copied the other.

13 likes in reply to #42 11mo
TW
t.wojcikTL222 Aug 2025#48
l.sarkissian, post #32: I read post #29 twice before replying, because I had assumed the opposite. If you are new and reading this thread for the answer to Filter needles: the answer is conditional, the conditions are in the third reply, and the rest of the thread is worth skipping. Go to post

Building on post #45 rather than restating it.

On Filter needles the community has more anecdote than the confidence in this thread implies, and I include my own contribution in that.

4 likes in reply to #32 11mo
AS
a.salcedoTL3Regular25 Aug 2025#49
c.serrano, post #7: Saving this. It is the version I will quote when the question comes round again. Go to post

The strongest argument against my own position on Filter needles, stated as well as I can state it, since nobody else has yet.

0 likes in reply to #7 11mo
KH
ka.haddadTL229 Aug 2025#50

This follows post #49 rather than contradicting it.

Sharps containers are a legal requirement for disposal in several jurisdictions and a sensible precaution everywhere. A rigid sealed container is the minimum.

Adding this to the thread rather than to the wiki, because I am not confident enough for the wiki.

0 likes 11mo
SC
s.cardosoTL21 Sep 2025#51
buffer_margin, post #24: On Filter needles: the maintained page in the documentation commons covers the general case with citations and a review date, which is more reliable than any reply here including this one. Go to post

Needle length: typical lengths for subcutaneous injection are 4-6 mm (short), 8 mm (standard), or 10-12 mm (longer). Longer needles are needed for deeper tissue or if you have abdominal adiposity.

0 likes in reply to #24 11mo
BP
b.petrovTL24 Sep 2025#52
t.steenkamp, post #36: Coming back to post #32, because the follow-up matters more than the original answer. I have three months of notes on Filter needles and the honest summary is that the trend is real and the week-to-week numbers are noise. I nearly drew the opposite conclusion from the first fortnight. Go to post

No notes. Posting so the count is not one.

2 likes in reply to #36 11mo
JT
j.teixeiraTL27 Sep 2025#53
This topic was closed 180 days after the last reply. Closing is automatic for quiet topics so that a settled answer does not collect new questions underneath it. If you have a follow-up, open a new topic and link back to this one — that keeps both readable and gives your question its own title.

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