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Lounge · Off topic · continued

Revisiting: The best-written scientific paper you have read posts 31–60

This is a continuation of a long topic, addressed by post number rather than by page. Start at post 1.

BM
buffer_marginTL3Regular14 Jun 2026#31
r.serrano, post #18: An observation about best-written scientific paper that I cannot explain and am posting anyway, on the principle that unexplained observations are more useful public than private. Go to post

Paper, same. I think it is that writing by hand is slow enough to make you decide what is worth recording.

20 likes in reply to #18 1mo
KA
k.agyemanTL214 Jun 2026#32

Practical note on best-written scientific paper: write down what you expect before you look. The number of times I have found what I went looking for is higher than chance would allow.

8 likes 1mo
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PSkarbekTL3Regular15 Jun 2026#33

I disagree with the framing of best-written scientific paper above, and I think it is a substantive disagreement rather than a terminological one. Setting out why, so it can be checked.

The reasoning depends on an assumption that is doing a lot of work and is never stated. If the assumption holds, the conclusion follows. I do not think it holds generally.

0 likes 1mo
BR
b.restrepoTL216 Jun 2026#34

That is true everywhere. The reference material that gets used is the material that answers a question you have at the moment you have it, and glamour has nothing to do with it.

I would rather say I do not know than round it up to an answer.

0 likes 1mo
DP
d.petrescuTL216 Jun 2026#35
n.boateng, post #24: Lounge question, no agenda: does anyone else keep a physical notebook for this rather than a file? Mine is more use than anything I have typed, and I cannot entirely explain why. Where I would look next, rather than where I would stop. Go to post

Before the thread moves on from best-written scientific paper — what is the sample size behind the claim? I am not being difficult; I have seen the same figure quoted from an n of four and from an n of four hundred.

27 likes in reply to #24 1mo
JH
j.hartmannTL217 Jun 2026#36
ms_holloway, post #17: A digression that keeps occurring to me: the most-linked documents here are the dullest ones. Nothing gets cited like the unit-arithmetic page. That has been true for the cases I have seen and I have not seen many. Go to post

Two things can be true about best-written scientific paper at once: the mechanism is plausible and the evidence for the size of the effect is thin. Most of the argument here is people defending the first against attacks on the second.

13 likes in reply to #17 1mo
CD
c.dahlbergTL217 Jun 2026 · edited#37

That is clearer than the version I had in my head. Thank you.

2 likes 1mo
IC
i.coelhoTL218 Jun 2026#38

Adjacent and interesting: you might post something about nutrition, bioavailability from a food perspective, or the sociology of weight. Adjacent to this community's core but not central.

That distinction has done more work for me than anything else in this category.

0 likes 1mo
VN
v.nascimentoTL218 Jun 2026#39

Worth separating best-written scientific paper as a question about the compound from best-written scientific paper as a question about the documentation. They get answered by different people and only one of them is answerable here.

9 likes 1mo
JB
j.baptistaTL219 Jun 2026#40
s.hartmann, post #7: This is the sort of exchange that makes the archive worth searching. Go to post

Where I have landed on best-written scientific paper, having got it wrong once in public: the direction is clear, the magnitude is not, and anyone quoting a precise magnitude has borrowed it from somewhere that did not measure it.

2 likes in reply to #7 1mo
JE
j.erdoganTL220 Jun 2026#41

Newer drugs and mechanisms: when a new drug launches or a new mechanism is discovered, the Lounge is a place to discuss the news and speculate before hard data exists.

Take the reasoning and check the arithmetic; I do not always get it right.

32 likes 1mo
NG
np_gilmoreTL3Nurse practitioner20 Jun 2026#42
b.osei, post #14: Right, and stated more narrowly than I would have dared to state it. Go to post

No notes. Posting so the count is not one.

0 likes in reply to #14 1mo
MV
m.vukovicTL221 Jun 2026#43

Science communication: if you come across an interesting science paper or article about peptides or metabolism, sharing it and discussing the idea is on-topic.

If anyone has run this properly I would rather read that than my own guess.

3 likes 1mo
MD
m.dalgaardTL3Regular21 Jun 2026#44

I would rather this thread reach "we do not know" about best-written scientific paper than reach a confident answer that nobody can support when asked.

11 likes 1mo
MO
m.onwukaTL222 Jun 2026#45
OB
owen.bradyTL4 Moderator22 Jun 2026#46
crossover_review, post #21: Something I have wondered without ever asking: is there a good reason the vocabulary in this field is so inconsistent between suppliers? Half the disagreements here start as terminology. Go to post

Personal stories: if you want to talk about what led you to this compound, your journey, or how the change has affected your life, the Lounge is the place for that.

1 like in reply to #21 1mo
SD
s.dialloTL223 Jun 2026#47

What would change my mind on best-written scientific paper is a second dataset collected by someone with no stake in the first. Until then I hold it loosely and I would rather say so than pretend to more.

6 likes 1mo
PP
peak_purityTL3Analytical chemist23 Jun 2026 · edited#48

Loosely related and not worth its own topic: the vocabulary here has leaked into how I read everything. I now notice when a press release gives a relative figure and no absolute one, which is most of the time.

If anyone can point at the primary source I would be grateful.

16 likes 1mo
EM
e.mbekiTL224 Jun 2026#49

That is a fair summary of where the discussion has got to.

17 likes 1mo
RH
revision_historyTL3Wiki editor24 Jun 2026#50

Best-written scientific paper is one of those subjects where the general answer and the answer for a specific case diverge, and the thread will go in circles until someone says which one is being asked for.

0 likes 1mo
MG
m.guerreroTL225 Jun 2026#51

Humour: light, relevant humour is welcome. Cruel humour targeting individuals or groups is not.

I have seen it go both ways, which is why I hedge.

22 likes 1mo
MM
methods_marginTL3Regular25 Jun 2026#52

On best-written scientific paper, I would rather understate and be corrected upward than overstate and be quoted. That is a house style here and it is a good one.

10 likes 1mo
KB
k.batistaTL226 Jun 2026#53
erratum_file, post #10: I changed my mind about best-written scientific paper after someone here asked me for the source and I could not produce one. That is worth saying out loud because it is the ordinary way it happens. Go to post

One caution on best-written scientific paper: everything above assumes the underlying documentation is what it claims to be. That assumption is doing real work and is rarely stated.

3 likes in reply to #10 1mo
CR
crossover_reviewTL3Regular26 Jun 2026#54

Community norms: if you want to discuss how the community should work (not moderation decisions, which go in Meta) the Lounge is a place for that casual discussion.

0 likes 1mo
AV
ai.vukovicTL227 Jun 2026#55

Best-written scientific paper was covered in the wiki last year and the page has a review date on it, which is a better starting point than my memory of a thread.

30 likes 1mo
GP
g.pemberton_ukTL3Regional · UK27 Jun 2026 · edited#56

Filing a mild objection to the consensus on best-written scientific paper. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit.

15 likes 30d
RS
r.szaboTL228 Jun 2026#57
ms_holloway, post #17: A digression that keeps occurring to me: the most-linked documents here are the dullest ones. Nothing gets cited like the unit-arithmetic page. That has been true for the cases I have seen and I have not seen many. Go to post

Agreed, and the corollary is that a place with no visible corrections is not a place with fewer errors.

5 likes in reply to #17 30d
DT
dexa_twice_yearlyTL3Regular28 Jun 2026#58

Off-topic but genuinely curious: how many people here came in through the analytics side rather than the practical side? The two groups seem to read completely different parts of the site.

Anyone with a larger sample, please post it.

1 like 29d
BA
b.adeyemiTL229 Jun 2026#59

Posting my best-written scientific paper numbers with the method attached so they can be discounted properly. Uncontrolled, unblinded, and collected by someone who wanted a particular answer.

11 likes 29d
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IMainwaringTL3Regular29 Jun 2026#60

The thing about best-written scientific paper that took me longest to accept is that a plausible mechanism is not evidence of an effect. It is a reason to look, not a result.

3 likes 28d